Articles with "exploring genetic" as a keyword



Exploring the genetic heterogeneity in major depression across diagnostic criteria

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Published in 2021 at "Molecular Psychiatry"

DOI: 10.1038/s41380-021-01231-w

Abstract: Major depressive disorder (MDD) is defined differently across genetic research studies and this may be a key source of heterogeneity. While previous literature highlights differences between minimal and strict phenotypes, the components contributing to this… read more here.

Keywords: depression; heterogeneity; major depression; depression phenotypes ... See more keywords

Exploring the Genetic Link Between Thyroid Dysfunction and Common Psychiatric Disorders: A Specific Hormonal or a General Autoimmune Comorbidity

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Published in 2022 at "Thyroid"

DOI: 10.1089/thy.2022.0304

Abstract: Background: The hypothalamus-pituitary-thyroid axis coordinates brain development and post-developmental function. Thyroid hormone variations, even within the normal range, have been associated with the risk of developing common psychiatric disorders, although the underlying mechanisms remain poorly… read more here.

Keywords: psychiatric disorders; thyroid; common psychiatric; exploring genetic ... See more keywords

Exploring genetic diversity in an Italian horse native breed to develop strategies for preservation and management

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Published in 2018 at "Journal of Animal Breeding and Genetics"

DOI: 10.1111/jbg.12357

Abstract: Genetic diversity is a key factor for both adaptation and response to selection. The loss of genetic diversity causes a decrease in individual fitness, and it has a dramatically negative effect on population lifespan in… read more here.

Keywords: horse; diversity; genetic diversity; native breed ... See more keywords

Exploring genetic interaction manifolds constructed from rich single-cell phenotypes

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Published in 2019 at "Science"

DOI: 10.1126/science.aax4438

Abstract: Manifold destiny Mapping of genetic interactions (GIs) is usually based on cell fitness as the phenotypic readout, which obscures the mechanistic origin of interactions. Norman et al. developed a framework for mapping and understanding GIs.… read more here.

Keywords: single cell; cell rna; exploring genetic; genetic interactions ... See more keywords

Exploring the genetic architecture of protein secretion in Komagataella phaffii (Pichia pastoris) for biotechnology applications

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Published in 2022 at "PLOS Biology"

DOI: 10.1371/journal.pbio.3001911

Abstract: Improvements to the production of proteins in industrial yeast species have largely relied on generating variation in a single genetic background. A new study in PLOS Biology leverages natural genetic variation to identify genes and… read more here.

Keywords: architecture protein; secretion komagataella; exploring genetic; genetic architecture ... See more keywords

Exploring the Genetic Underpinnings of Bullying: A Contemporary Analysis of Scholarly Investigations

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Published in 2024 at "Society"

DOI: 10.33019/society.v12i2.673

Abstract: Since the early 21st century, bullying has been a central focus for scholars, with various forms, such as relational, physical, cyber, and social bullying, receiving extensive attention. However, the role of genetic and hereditary factors… read more here.

Keywords: genetics; underpinnings bullying; bullying behaviors; exploring genetic ... See more keywords

Exploring the genetic profiles linked to senescence in thyroid tumors: insights on predicting disease progression and immune responses

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Published in 2025 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2025.1545656

Abstract: Introduction Thyroid cancer (THCA) is the most common endocrine tumor. Research on Cell Senescence Associated Genes (CSAGs), which impact many cancers, remains limited in the THCA field. Methods In this study, we downloaded THCA sample… read more here.

Keywords: senescence; analysis; exploring genetic; model ... See more keywords

Exploring the Genetic Variability and Potential Correlations Between Nutritional Quality and Agro-Physiological Traits in Kabuli Chickpea Germplasm Collection (Cicer arietinum L.)

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Published in 2022 at "Frontiers in Plant Science"

DOI: 10.3389/fpls.2022.905320

Abstract: Chickpea is an important source of plant-based protein and mineral elements such as iron (Fe) and zinc (Zn). The development of superior high-yielding germplasm with high nutritional value becomes central for any breeding program. Chickpea… read more here.

Keywords: quality; exploring genetic; germplasm; correlation ... See more keywords

Exploring the Genetic Structure and Phylogeographic Patterns of the Copepod Genus Eurytemora in Europe

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Published in 2024 at "Diversity"

DOI: 10.3390/d16080483

Abstract: The genus Eurytemora is a diverse group of copepods found in coastal, estuarine, brackish, and freshwater environments. The main research has focused on Eurytemora affinis (Poppe, 1880) and revealed it to be a species complex.… read more here.

Keywords: genus eurytemora; phylogeographic patterns; exploring genetic; structure phylogeographic ... See more keywords

Psoriasis and Seasonality: Exploring the Genetic and Epigenetic Interactions

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Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms252111670

Abstract: Psoriasis is a multifactorial, chronic, and inflammatory disease that severely impacts patients’ quality of life. The disease is caused by genetic irregularities affected by epigenetic and environmental factors. Some of these factors may include seasonal… read more here.

Keywords: genetic epigenetic; psoriasis seasonality; seasonality exploring; exploring genetic ... See more keywords

Exploring the Genetic Potential for Multi-Resistance to Rust and Other Coffee Phytopathogens in Breeding Programs

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Published in 2025 at "Plants"

DOI: 10.3390/plants14030391

Abstract: The application of marker-assisted selection in coffee breeding programs accelerates the identification and concentration of target alleles, being essential for developing cultivars resistant to multiple diseases. In this study, a population was developed from artificial… read more here.

Keywords: resistance; coffee; leaf miner; exploring genetic ... See more keywords