Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors.
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DOI: 10.1021/acsmedchemlett.7b00229
Abstract: We report the synthesis, biological evaluation, and structural study of a series of substituted heteroaryl-pyrazole carboxylic acid derivatives. These compounds have been developed as inhibitors of specific isoforms of carbonic anhydrase (CA), with potential as… read more here.
Keywords: carbonic anhydrase; exploring heteroaryl; pyrazole carboxylic; carboxylic acids ... See more keywords