Exploring mechanism of enzyme catalysis by on-chip transient kinetics coupled with global data analysis and molecular modeling
Sign Up to like & getrecommendations! Published in 2021 at "Chem"
DOI: 10.1016/j.chempr.2021.02.011
Abstract: Summary The ability to engineer enzymes for industrial and biomedical applications is primarily limited by a paucity of mechanistic understanding. To gain insight into the mechanisms of enzyme catalysis, one must screen enormous numbers of… read more here.
Keywords: transient; mechanism enzyme; transient kinetics; exploring mechanism ... See more keywords
Exploring the mechanism of MP gel against skin photoaging based on network pharmacology, molecular docking, and experimental validation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.15542
Abstract: Long‐term and high exposure to UV radiation can lead to the development of skin photoaging diseases. Therefore, there is an ongoing need for more natural and safe drugs to prevent or treat skin photoaging diseases. read more here.
Keywords: gel skin; pharmacology; exploring mechanism; mechanism gel ... See more keywords
Exploring the Mechanism of Inhibition of Au Nanoparticles on the Aggregation of Amyloid-β(16-22) Peptides at the Atom Level by All-Atom Molecular Dynamics
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19061815
Abstract: The abnormal self-assembly of the amyloid-β peptide into toxic β-rich aggregates can cause Alzheimer’s disease. Recently, it has been shown that small gold nanoparticles (AuNPs) inhibit Aβ aggregation and fibrillation by slowing down the nucleation… read more here.
Keywords: mechanism inhibition; atom molecular; exploring mechanism; molecular dynamics ... See more keywords