Exploring methods to expedite the recording of CEST datasets using selective pulse excitation.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of magnetic resonance"
DOI: 10.1016/j.jmr.2018.04.013
Abstract: Chemical Exchange Saturation Transfer (CEST) has emerged as a powerful tool for studies of biomolecular conformational exchange involving the interconversion between a major, visible conformer and one or more minor, invisible states. Applications typically entail… read more here.
Keywords: expedite recording; methods expedite; exploring methods; recording cest ... See more keywords
Exploring Methods of Targeting Histone Methyltransferases and Their Applications in Cancer Therapeutics.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical biology"
DOI: 10.1021/acschembio.2c00062
Abstract: Histone methyltransferases (HMTs) are enzymes that catalyze the methylation of lysine or arginine residues of histone proteins, a key post-translational modification (PTM). Aberrant expression or activity of these enzymes can lead to abnormal histone methylation… read more here.
Keywords: exploring methods; histone methyltransferases; histone; methods targeting ... See more keywords