Exploring mitochondrial cholesterol signalling for therapeutic intervention in neurological conditions
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14697
Abstract: The pharmacological targeting of cholesterol levels continues to generate interest due to the undoubted success of therapeutic agents, such as statins, in extending life expectancy by modifying the prognosis of diseases associated with the impairment… read more here.
Keywords: cholesterol signalling; signalling therapeutic; cholesterol; exploring mitochondrial ... See more keywords
Complexome Profiling—Exploring Mitochondrial Protein Complexes in Health and Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.796128
Abstract: Complexome profiling (CP) is a state-of-the-art approach that combines separation of native proteins by electrophoresis, size exclusion chromatography or density gradient centrifugation with tandem mass spectrometry identification and quantification. Resulting data are computationally clustered to… read more here.
Keywords: complexome profiling; mitochondrial protein; exploring mitochondrial; profiling exploring ... See more keywords