Exploring Novel Coumarin‐Tethered Bis‐Triazoles: Apoptosis Induction in Human Pancreatic Cancer Cells, Antimicrobial Effects, and Molecular Modelling Investigations
Sign Up to like & getrecommendations! Published in 2024 at "Chemmedchem"
DOI: 10.1002/cmdc.202400297
Abstract: In the present study, we identified that two representative compounds (7 c and 9 f) of our newly synthesized coumarin‐tagged bis‐triazoles induced apoptosis in human pancreatic cells (PANC‐1) by caspase 3/7mediated pathway. Both 7 c and 9 f (IC50=7.15±1.19… read more here.
Keywords: cancer; human pancreatic; coumarin; bis triazoles ... See more keywords
Exploring the novel structure, transportable capacity and thermodynamic properties of TiH2 hydrogen storage material
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Energy Research"
DOI: 10.1002/er.5260
Abstract: We apply the first‐principles calculations to study the structure, elastic modulus, Debye temperature and heat capacity of four TiH2. The results show that one new orthorhombic (Pnma) TiH2 is predicted. The tetragonal (I4mmm) TiH2 is… read more here.
Keywords: novel structure; capacity; tih2; exploring novel ... See more keywords
Exploring novel deformation mechanisms in aluminum–copper alloys using in situ 4D nanomechanical testing
Sign Up to like & getrecommendations! Published in 2019 at "Acta Materialia"
DOI: 10.1016/j.actamat.2019.07.016
Abstract: Abstract Even after nearly a century of extensive use of aluminum alloys in structural applications, our understanding of such precipitation-strengthened materials is far from complete. With the advent of next generation advanced characterization techniques, our… read more here.
Keywords: nanomechanical testing; situ nanomechanical; deformation mechanisms; exploring novel ... See more keywords
Exploring a novel approach to manipulating plasmon-induced transparency
Sign Up to like & getrecommendations! Published in 2018 at "Optics Communications"
DOI: 10.1016/j.optcom.2018.07.018
Abstract: Abstract Plasmon-induced transparency (PIT) effect is an important optical phenomenon in plasmonic structures. In this paper, we design a plasmonic structure to realize the manipulation of PIT simply by varying the angle of the ellipse.… read more here.
Keywords: induced transparency; exploring novel; pit effect; plasmon induced ... See more keywords
Exploring novel bismuth-based materials for energy storage applications
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Materials Chemistry C"
DOI: 10.1039/c8tc02801j
Abstract: The increasing consumption of compact electronics impels us to design high-performance dielectric energy storage materials. Bi0.5K0.5TiO3-based materials, which have been ignored thus far in energy storage applications, possess an ultrahigh stored energy density (WS =… read more here.
Keywords: energy; exploring novel; energy storage; storage applications ... See more keywords
Exploring novel functions of BACH2 in the acquisition of antigen-specific antibodies.
Sign Up to like & getrecommendations! Published in 2022 at "International immunology"
DOI: 10.1093/intimm/dxac065
Abstract: BACH2 [BTB (broad-complex, tramtrak and bric à brac) and CNC (cap 'n' collar) homolog 2] is known as a transcriptional repressor and broadly functions in regulating immune cell differentiation. Here, we focus on BACH2 function… read more here.
Keywords: novel functions; bach2 acquisition; acquisition antigen; bach2 ... See more keywords
Exploring novel immunotherapy biomarker candidates induced by cancer deformation
Sign Up to like & getrecommendations! Published in 2024 at "PLOS ONE"
DOI: 10.1371/journal.pone.0303433
Abstract: Triple-negative breast cancer (TNBC) demands urgent attention for the development of effective treatment strategies due to its aggressiveness and limited therapeutic options [1]. This research is primarily focused on identifying new biomarkers vital for immunotherapy,… read more here.
Keywords: cancer; induced cancer; immunotherapy; cancer deformation ... See more keywords
Exploring novel antitubercular agents: Innovative design of 2,3-diaryl-quinoxalines targeting DprE1 for effective tuberculosis treatment
Sign Up to like & getrecommendations! Published in 2024 at "Open Chemistry"
DOI: 10.1515/chem-2024-0086
Abstract: Abstract The rising instances of drug resistance in Mycobacterium tuberculosis strains pose a significant global health challenge. Conventional tuberculosis (TB) treatments, which typically involve multiple antibiotics, face hurdles like drug resistance, reduced effectiveness, and heightened… read more here.
Keywords: treatment; tuberculosis; drug; targeting dpre1 ... See more keywords
Exploring the Novel Computational Drug Target and Associated Key Pathways of Oral Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Current Issues in Molecular Biology"
DOI: 10.3390/cimb44080244
Abstract: Oral cancer (OC) is a serious health concern that has a high fatality rate. The oral cavity has seven kinds of OC, including the lip, tongue, and floor of the mouth, as well as the… read more here.
Keywords: oral cancer; analysis; common degs; drug ... See more keywords
Scalp Microbiome and Dandruff—Exploring Novel Biobased Esters
Sign Up to like & getrecommendations! Published in 2024 at "Cosmetics"
DOI: 10.3390/cosmetics11050174
Abstract: Recent data suggest that dandruff might be associated with dysbiosis of the scalp microbiome. This mini review summarizes the microbiome changes seen with the dandruff condition, as well as different solutions for dandruff control and… read more here.
Keywords: microbiome dandruff; dandruff exploring; novel biobased; scalp microbiome ... See more keywords
Advancements in Diagnosing Talaromycosis: Exploring Novel Strategies and Emerging Technologies
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Fungi"
DOI: 10.3390/jof11060434
Abstract: Talaromycosis (TM) is an invasive fungal infection caused by Talaromyces marneffei (T. marneffei). It has high morbidity and mortality rates, particularly among immunocompromised people. Globally, approximately 17,300 cases and 4900 deaths are reported annually. TM… read more here.
Keywords: novel strategies; talaromycosis; advancements diagnosing; talaromycosis exploring ... See more keywords