Exploring RNA G-quadruplex in the rabies virus genome and its potential against RABV infection.
Sign Up to like & getrecommendations! Published in 2025 at "Chemical science"
DOI: 10.1039/d5sc04344a
Abstract: Rabies virus (RABV) is a prototypical neurotropic RNA virus that can cause rabies with an almost 100% fatality rate. Despite great efforts having been made to identify an effective therapeutic target of rabies, the host… read more here.
Keywords: rabies virus; rabv infection; exploring rna; rabv ... See more keywords
Exploring RNA destabilization mechanisms in biomolecular condensates through atomistic simulations
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1101/2024.09.13.612876
Abstract: Biomolecular condensates are currently recognized to play a key role in organizing cellular space and in orchestrating biochemical processes. Despite an increasing interest in characterizing their internal organization at the molecular scale, not much is… read more here.
Keywords: condensates atomistic; rna destabilization; exploring rna; biomolecular condensates ... See more keywords
Exploring the RNA Gap for Improving Diagnostic Yield in Primary Immunodeficiencies
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2019.01204
Abstract: Challenges in diagnosing primary immunodeficiency are numerous and diverse, with current whole-exome and whole-genome sequencing approaches only able to reach a molecular diagnosis in 25–60% of cases. We assess these problems and discuss how RNA-focused… read more here.
Keywords: yield primary; improving diagnostic; diagnostic yield; rna gap ... See more keywords