Cancer cells hijack RNA processing to rewrite the message
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Society Transactions"
DOI: 10.1042/bst20220621
Abstract: Typically, cancer is thought to arise due to DNA mutations, dysregulated transcription and/or aberrant signalling. Recently, it has become clear that dysregulated mRNA processing, mRNA export and translation also contribute to malignancy. RNA processing events… read more here.
Keywords: cancer; processing; export translation; cells hijack ... See more keywords
Multipurpose RNA maturation factors dysregulate multiple mRNA processing steps simultaneously and provide new therapeutic opportunities
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DOI: 10.1080/15476286.2025.2503040
Abstract: ABSTRACT mRNAs undergo a series of chemical modifications to become competent for nuclear export and translation. This is referred to as mRNA maturation or processing and includes capping, splicing, and 3’end formation. These steps can… read more here.
Keywords: mrna processing; maturation; export translation; processing ... See more keywords
eIF4E orchestrates mRNA processing, RNA export and translation to modify specific protein production
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DOI: 10.1080/19491034.2024.2360196
Abstract: ABSTRACT The eukaryotic translation initiation factor eIF4E acts as a multifunctional factor that simultaneously influences mRNA processing, export, and translation in many organisms. Its multifactorial effects are derived from its capacity to bind to the… read more here.
Keywords: mrna processing; translation; export translation; eif4e ... See more keywords