Exposed and Sequestered Antigens in Testes and Their Protection by Regulatory T Cell-Dependent Systemic Tolerance
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DOI: 10.3389/fimmu.2022.809247
Abstract: Continuous exposure of tissue antigen (Ag) to the autoantigen-specific regulatory T cells (Treg) is required to maintain Treg-dependent systemic tolerance. Thus, testis autoantigens, previously considered as sequestered, may not be protected by systemic tolerance. We… read more here.
Keywords: dependent systemic; exposed sequestered; testis; tolerance ... See more keywords