Interpretation of Drug Interaction Using Systemic and Local Tissue Exposure Changes
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DOI: 10.3390/pharmaceutics12050417
Abstract: Systemic exposure of a drug is generally associated with its pharmacodynamic (PD) effect (e.g., efficacy and toxicity). In this regard, the change in area under the plasma concentration-time curve (AUC) of a drug, representing its… read more here.
Keywords: tissue exposure; exposure changes; exposure; drug ... See more keywords