Repeated exposure to chlorpyrifos is associated with a dose-dependent chronic neurobehavioral deficit in adult rats.
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DOI: 10.1016/j.neuro.2022.03.011
Abstract: Organophosphate (OP) chemicals include commonly used pesticides and chemical warfare agents, and mechanistically they are potent inhibitors of the cholinesterase (ChE) enzyme. Epidemiological studies report long-term neuropsychiatric issues, including depression and cognitive impairments in OP-exposed… read more here.
Keywords: dose dependent; chlorpyrifos associated; adult rats; long term ... See more keywords