Glioma mutational signatures associated with haloalkane exposure are enriched in firefighters
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DOI: 10.1002/cncr.35732
Abstract: Glioma is the most common malignant primary brain tumor and is associated with significant morbidity and mortality. Modifiable risk factors remain unidentified. New advances in exposure assessment, genomic analyses, and statistical techniques permit more accurate… read more here.
Keywords: glioma mutational; associated haloalkane; haloalkane exposure; signatures associated ... See more keywords
Exposure enriched outcome dependent designs for longitudinal studies of gene-environment interaction.
Sign Up to like & getrecommendations! Published in 2017 at "Statistics in medicine"
DOI: 10.1002/sim.7332
Abstract: Joint effects of genetic and environmental factors have been increasingly recognized in the development of many complex human diseases. Despite the popularity of case-control and case-only designs, longitudinal cohort studies that can capture time-varying outcome… read more here.
Keywords: longitudinal studies; exposure enriched; exposure; designs longitudinal ... See more keywords