Postnatal exposure to fluoxetine led to cognitive‐emotional alterations and decreased parvalbumin positive neurons in the hippocampus of juvenile Wistar rats
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Developmental Neuroscience"
DOI: 10.1002/jdn.10139
Abstract: The exposure to selective serotonin reuptake inhibitors (SSRIs) during development results in behavioural impairment in adulthood in humans and animal models. Indeed, serotonergic overexpression in early life leads to structural and functional changes in brain… read more here.
Keywords: hippocampus juvenile; exposure; parvalbumin positive; postnatal exposure ... See more keywords
Prenatal exposure to fluoxetine modulates emotionality and aversive memory in male and female rat offspring
Sign Up to like & getrecommendations! Published in 2022 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000705
Abstract: During pregnancy, women are prone to depression, for which selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine, are usually the first-line treatment. However, fluoxetine can cross the placental barrier and affect fetuses, causing changes in… read more here.
Keywords: fluoxetine; aversive memory; male female; exposure fluoxetine ... See more keywords