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   Articles with "exposure limits" as a keyword



Submarine exposure guideline recommendations for carbon dioxide based on the prenatal developmental effects of exposure in rats.

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recommendations! Published in 2019 at "Birth defects research"

DOI: 10.1002/bdr2.1417

Abstract: BACKGROUND To protect crewmember health, the U.S. Navy sets exposure limits for more than 200 components of submarine atmospheres. The addition of females to nuclear submarines required a reevaluation of these exposure limits, originally established… read more here.

Keywords: co2; carbon dioxide; exposure limits; exposure ... See more keywords

Approaches for setting occupational exposure limits in the pharmaceutical industry

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recommendations! Published in 2021 at "Journal of Applied Toxicology"

DOI: 10.1002/jat.4218

Abstract: The use of pharmaceutical drugs has provided a cure for many diseases. However, unintended exposure to drugs in the manufacturing workplace can cause significant health hazards to workers. It is important to protect the workforce… read more here.

Keywords: occupational exposure; exposure limits; limits pharmaceutical; approaches setting ... See more keywords

Derivation of occupational exposure limits: Differences in methods and protection levels

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recommendations! Published in 2022 at "Journal of Applied Toxicology"

DOI: 10.1002/jat.4307

Abstract: Frameworks for deriving occupational exposure limits (OELs) and OEL‐analogue values (such as derived‐no‐effect levels [DNELs]) in various regulatory areas in the EU and at national level in Germany were analysed. Reasons for differences between frameworks… read more here.

Keywords: protection; assessment factors; occupational exposure; protection levels ... See more keywords

Identifying nonhazardous substances in pharmaceutical manufacturing and setting default health‐based exposure limits (HBELs)

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recommendations! Published in 2022 at "Journal of Applied Toxicology"

DOI: 10.1002/jat.4323

Abstract: Contract Development and Manufacturing Organizations (CDMOs) that manufacture large, diverse portfolio of chemical and pharmaceutical substances require pragmatic risk‐based decisions with respect to the safe carry‐over between different chemical entities, as well as for worker… read more here.

Keywords: default; health based; based exposure; nonhazardous substances ... See more keywords

Setting evidence‐based occupational exposure limits for manganese

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recommendations! Published in 2017 at "Neurotoxicology"

DOI: 10.1016/j.neuro.2016.08.005

Abstract: HighlightsOELs for Mn are based on subtle neurological changes as the key toxicity endpoint.These changes are limited in particular by unreliable exposure estimates.Clinical significance of subclinical cognitive or neuromotor changes is unknown.8‐h TWAs for respirable… read more here.

Keywords: exposure limits; exposure; evidence; health ... See more keywords

The role of toxic stimuli combinations in determining safe exposure limits

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recommendations! Published in 2018 at "Toxicology Reports"

DOI: 10.1016/j.toxrep.2018.10.010

Abstract: This editorial addresses the effects of toxic stimuli combinations on determination of safe Exposure Limits. Examination of thousands of Medline abstracts showed typically that combinations of toxic stimuli can produce damage even when the exposure… read more here.

Keywords: exposure limits; stimuli combinations; exposure; toxic stimuli ... See more keywords

A review of OSHA-permissible exposure limits for occupational carcinogens in relation to quantitative risk assessments based on epidemiological findings

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recommendations! Published in 2024 at "Journal of Occupational and Environmental Hygiene"

DOI: 10.1080/15459624.2024.2406234

Abstract: Abstract A very small proportion of all chemicals in commerce have occupational exposure limits (OELs) based on quantitative risk assessments which require estimates of exposure-response relationships (XRs). For only 18 of the 94 chemicals declared… read more here.

Keywords: quantitative risk; exposure limits; permissible exposure; risk assessments ... See more keywords
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Occupational exposure limits for manufactured nanomaterials, a systematic review

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recommendations! Published in 2017 at "Nanotoxicology"

DOI: 10.1080/17435390.2016.1262920

Abstract: Abstract Background: The toxicological properties of manufactured nanomaterials (MNMs) can be different from their bulk-material and uncertainty remains about the adverse health effects they may have on humans. Proposals for OELs have been put forward… read more here.

Keywords: manufactured nanomaterials; systematic review; exposure limits; exposure ... See more keywords

23 Applied occupational hygiene in pharmaceutical industries

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recommendations! Published in 2024 at "Annals of Work Exposures and Health"

DOI: 10.1093/annweh/wxae035.272

Abstract: Occupational hygiene is the highest priority in pharmaceutical industries. Potent Active Pharmaceutical Ingredients (APIs) with nanograms per cubic meter exposure limits are handled. The API manufacturing plant uses highly hazardous chemicals like methylene chloride and… read more here.

Keywords: exposure; pharmaceutical industries; api exposure; exposure limits ... See more keywords

Bivariate Left-Censored Measurements in Biomonitoring: A Bayesian Model for the Determination of Biological Limit Values Based on Occupational Exposure Limits

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recommendations! Published in 2017 at "Annals Of Work Exposures and Health"

DOI: 10.1093/annweh/wxx031

Abstract: Biological limit values (BLV) are often determined from the occupational exposure limits (OEL) in modelling biological data obtained on a number of exposed subjects based on measurements of air exposure. In order to obtain such… read more here.

Keywords: exposure limits; exposure; method; biological limit ... See more keywords

Considerations for Development of Exposure Limits for Chemicals Encountered During Aircraft Operation.

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recommendations! Published in 2020 at "Military medicine"

DOI: 10.1093/milmed/usz318

Abstract: BACKGROUND Military aircrews' health status is critical to their mission readiness, as they perform physically and cognitively demanding tasks in nontraditional work environments. Research Objectives: Our objective is to develop a broad operational risk assessment… read more here.

Keywords: chemicals encountered; exposure limits; exposure; development exposure ... See more keywords