Sevoflurane exposure has minimal effect on cognitive function and does not alter microglial activation in adult monkeys
Sign Up to like & getrecommendations! Published in 2019 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2018.12.008
Abstract: HighlightsAn 8‐hour exposure to sevoflurane did not cause an increase in neuroinflammation as measured by [18F]‐FEPPA in aged monkeys.Extended exposure to sevoflurane had minimal impact on the performance of aged monkeys trained on cognitive test… read more here.
Keywords: adult; exposure sevoflurane; anesthesia; exposure ... See more keywords
Exposure to sevoflurane anesthesia during development does not impair aspects of attention during adulthood in rats.
Sign Up to like & getrecommendations! Published in 2017 at "Neurotoxicology and teratology"
DOI: 10.1016/j.ntt.2016.11.010
Abstract: Exposure to general anesthetic agents during development has been associated with neurotoxicity and long-term behavioral impairments in rodents and non-human primates. The phenotype of anesthetic-induced cognitive impairment has a robust learning and memory component, however… read more here.
Keywords: anesthetic induced; anesthesia; exposure sevoflurane; attention ... See more keywords
Neonatal exposure to sevoflurane induces adolescent neurobehavioral dysfunction by interfering with hippocampal glycerophoslipid metabolism in rats.
Sign Up to like & getrecommendations! Published in 2022 at "Cerebral cortex"
DOI: 10.1093/cercor/bhac185
Abstract: Sevoflurane exposure in the neonatal period causes long-term developmental neuropsychological dysfunction, including memory impairment and anxiety-like behaviors. However, the molecular mechanisms underlying such effects have not been fully elucidated. In this study, we investigated the… read more here.
Keywords: metabolism; neonatal exposure; dysfunction; exposure sevoflurane ... See more keywords