Long-term exposure to TNF-α leads human skin fibroblasts to a p38 MAPK- and ROS-mediated premature senescence
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DOI: 10.1007/s10522-018-9753-9
Abstract: Tumor necrosis factor α (TNF-α) is an inflammatory mediator overexpressed in the skin as a response to ultraviolet radiation, as well as in chronic non-healing wounds. On the other hand, senescent fibroblasts have been shown… read more here.
Keywords: p38 mapk; premature senescence; tnf; exposure tnf ... See more keywords