Relationship between exposure to treosulfan and its monoepoxytransformer – An insight from population pharmacokinetic study in pediatric patients before hematopoietic stem cell transplantation
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DOI: 10.1016/j.ejps.2018.04.036
Abstract: &NA; Treosulfan (TREO), a structural analog of busulfan, is currently studied as a myeloablative agent in conditioning regimens before hematopoietic stem cell transplantation in pediatric patients. High exposure to TREO (>1650 mg*h/mL) might be related… read more here.
Keywords: population pharmacokinetic; treo; exposure; exposure treo ... See more keywords