Two distinct skeletal muscle microRNA signatures revealing the complex mechanism of sporadic ALS.
Sign Up to like & getrecommendations! Published in 2021 at "Acta neurologica Belgica"
DOI: 10.1007/s13760-021-01743-w
Abstract: Skeletal muscle pathology is thought to have an important role in the onset and/or progression of amyotrophic lateral sclerosis (ALS), which is a neurodegenerative disorder characterized by progressive muscle weakness. Since miRNAs are recognized as… read more here.
Keywords: skeletal muscle; muscle; mirnas patients; expressed mirnas ... See more keywords
Bioinformatic screening for candidate biomarkers and their prognostic values in endometrial cancer
Sign Up to like & getrecommendations! Published in 2020 at "BMC Genetics"
DOI: 10.1186/s12863-020-00898-4
Abstract: Background Endometrial cancer is a common gynecological cancer with annually increasing incidence worldwide. However, the biomarkers that provide prognosis and progression for this disease remain elusive. Results Two eligible human endometrial cancer datasets (GSE17025 and… read more here.
Keywords: screening candidate; bioinformatic screening; expressed mirnas; endometrial cancer ... See more keywords
Infrequently expressed miRNAs influence survival after diagnosis with colorectal cancer
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19863
Abstract: Half of miRNAs expressed in colorectal tissue are expressed < 50% of the population. Many infrequently expressed miRNAs have low levels of expression. We hypothesize that less frequently expressed miRNAs, when expressed at higher levels,… read more here.
Keywords: infrequently expressed; mir; expressed mirnas; cancer ... See more keywords
Identification of differentially expressed miRNAs and miRNA-targeted genes in bladder cancer
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.24441
Abstract: Background Differentially expressed genes and their post-transcriptional regulator-microRNAs (miRNAs), are potential keys to pioneering cancer diagnosis and treatment. The aim of this study was to investigate how the miRNA-mRNA interactions might affect the tumorigenesis of… read more here.
Keywords: bladder cancer; expressed mirnas; cancer; differentially expressed ... See more keywords
Identifying the Potential Differentially Expressed miRNAs and mRNAs in Osteonecrosis of the Femoral Head Based on Integrated Analysis
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Interventions in Aging"
DOI: 10.2147/cia.s289479
Abstract: Purpose Osteonecrosis of the femoral head is a common disease of the hip that leads to severe pain or joint disability. We aimed to identify potential differentially expressed miRNAs and mRNAs in osteonecrosis of the… read more here.
Keywords: differentially expressed; expressed mirnas; femoral head; mirnas mrnas ... See more keywords
Serum extracellular vesicle MicroRNAs as candidate biomarkers for acute rejection in patients subjected to liver transplant
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1015049
Abstract: Acute rejection (AR) is a common and grave complication of liver transplantation (LT). The diagnosis of AR is challenging because it has nonspecific clinical features and requires invasive procedures. Since extracellular vesicles (EVs) are promising… read more here.
Keywords: patients subjected; liver transplant; serum; expressed mirnas ... See more keywords
Differential Expression of MicroRNAs in Leprosy Skin Lesions
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.01035
Abstract: Leprosy, a chronic infectious disease caused by Mycobacterium leprae, is a major public health problem in poor and developing countries of the Americas, Africa, and Asia. MicroRNAs (miRNAs), which are small non-coding RNAs (18–24 nucleotides),… read more here.
Keywords: hsa mir; hsa; expressed mirnas; expression ... See more keywords
Differentially Expressed miRNAs in Ulcerative Colitis and Crohn’s Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.865777
Abstract: Differential microRNA (miRNA or miR) regulation is linked to the development and progress of many diseases, including inflammatory bowel disease (IBD). It is well-established that miRNAs are involved in the differentiation, maturation, and functional control… read more here.
Keywords: expressed mirnas; crohn disease; differentially expressed; colitis crohn ... See more keywords
Small RNA deep sequencing reveals novel miRNAs in peripheral blood mononuclear cells from patients with IgA nephropathy
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2020.11405
Abstract: Peripheral blood mononuclear cells (PBMCs) contribute to the deposition of immunoglobulin A (IgA) and progression of IgA nephropathy (IgAN). This study was performed to identify novel microRNAs (miRNAs/miRs) associated with IgAN. Small RNAs were isolated… read more here.
Keywords: blood mononuclear; mononuclear cells; iga nephropathy; expressed mirnas ... See more keywords