Characterization of calbindin D28k expressing interneurons in the ventral horn of the mouse spinal cord
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Dynamics"
DOI: 10.1002/dvdy.24601
Abstract: Background: Expression of the calcium binding protein, calbindin (CB), is well established as a hallmark of Renshaw cells, a class of interneurons found in spatially restricted areas in the ventral spinal cord that directly modulate… read more here.
Keywords: expressing interneurons; interneurons ventral; expression; ventral horn ... See more keywords
Axonal sprouting in commissurally projecting parvalbumin‐expressing interneurons
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24011
Abstract: Previous research has shown that in vivo on‐demand optogenetic stimulation of inhibitory interneurons expressing parvalbumin (PV) is sufficient to suppress seizures in a mouse model of temporal lobe epilepsy (TLE). Surprisingly, this intervention was capable… read more here.
Keywords: expressing interneurons; commissurally projecting; axonal sprouting; parvalbumin ... See more keywords
Opposing Ventral Striatal Medium Spiny Neuron Activities Shaped by Striatal Parvalbumin-Expressing Interneurons during Goal-Directed Behaviors.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.107829
Abstract: Medium spiny neurons (MSNs) of mice show opposing activities upon the initiation of a food-seeking lever press task. Ventromedial striatal (VMS)-MSNs are inhibited but ventrolateral striatal (VLS)-MSNs are activated; these activities mediate action selection and… read more here.
Keywords: expressing interneurons; striatal parvalbumin; parvalbumin expressing; medium spiny ... See more keywords
Dendritic inhibition differentially regulates excitability of dentate gyrus parvalbumin-expressing interneurons and granule cells
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-13533-3
Abstract: Fast-spiking parvalbumin-expressing interneurons (PVIs) and granule cells (GCs) of the dentate gyrus receive layer-specific dendritic inhibition. Its impact on PVI and GC excitability is, however, unknown. By applying whole-cell recordings, GABA uncaging and single-cell-modeling, we… read more here.
Keywords: expressing interneurons; inhibition; parvalbumin expressing; dendritic inhibition ... See more keywords
Parvalbumin-expressing interneurons can act solo while somatostatin-expressing interneurons act in chorus in most cases on cortical pyramidal cells
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12958-4
Abstract: Neural circuits in the cerebral cortex consist primarily of excitatory pyramidal (Pyr) cells and inhibitory interneurons. Interneurons are divided into several subtypes, in which the two major groups are those expressing parvalbumin (PV) or somatostatin… read more here.
Keywords: pyr; expressing interneurons; interneurons act; som neurons ... See more keywords
Intersectional strategy to study cortical inhibitory parvalbumin-expressing interneurons
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-52901-y
Abstract: Parvalbumin-expressing (PV) interneurons are key neuronal elements to a global excitatory-inhibitory balance in normal cortical functioning. To better understand the circuit functions of PV interneurons, reliable animal models are needed. This study investigated the sensitivity… read more here.
Keywords: tdtomato; parvalbumin expressing; expressing interneurons; cre ... See more keywords
Fragile X cortex is characterized by decreased parvalbumin-expressing interneurons.
Sign Up to like & getrecommendations! Published in 2024 at "Cerebral cortex"
DOI: 10.1093/cercor/bhae103
Abstract: Fragile X syndrome is a genetic neurodevelopmental disorder caused by a mutation of the fragile X messenger ribonucleoprotein 1 (FMR1) gene in the X chromosome. Many fragile X syndrome cases present with autism spectrum disorder… read more here.
Keywords: disorder; parvalbumin expressing; expressing interneurons; fragile syndrome ... See more keywords
Loss of Mecp2 Causes Atypical Synaptic and Molecular Plasticity of Parvalbumin-Expressing Interneurons Reflecting Rett Syndrome–Like Sensorimotor Defects
Sign Up to like & getrecommendations! Published in 2018 at "eNeuro"
DOI: 10.1523/eneuro.0086-18.2018
Abstract: Abstract Rett syndrome (RTT) is caused in most cases by loss-of-function mutations in the X-linked gene encoding methyl CpG-binding protein 2 (MECP2). Understanding the pathological processes impacting sensory-motor control represents a major challenge for clinical… read more here.
Keywords: expressing interneurons; rett syndrome; mecp2; motor ... See more keywords
Activity-Dependent Ectopic Spiking in Parvalbumin-Expressing Interneurons of the Neocortex
Sign Up to like & getrecommendations! Published in 2024 at "eNeuro"
DOI: 10.1523/eneuro.0314-23.2024
Abstract: Canonically, action potentials of most mammalian neurons initiate at the axon initial segment (AIS) and propagate bidirectionally: orthodromically along the distal axon and retrogradely into the soma and dendrites. Under some circumstances, action potentials may… read more here.
Keywords: activity dependent; parvalbumin expressing; expressing interneurons; ectopic spiking ... See more keywords
A Role for Matrix Metalloproteases in Antidepressant Efficacy
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2019.00117
Abstract: Major depressive disorder is a debilitating condition that affects approximately 15% of the United States population. Though the neurophysiological mechanisms that underlie this disorder are not completely understood, both human and rodent studies suggest that… read more here.
Keywords: expressing interneurons; pyramidal cell; matrix; antidepressant efficacy ... See more keywords
Selective Enrichment of Munc13-2 in Presynaptic Active Zones of Hippocampal Pyramidal Cells That Innervate mGluR1α Expressing Interneurons
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Synaptic Neuroscience"
DOI: 10.3389/fnsyn.2021.773209
Abstract: Selective distribution of proteins in presynaptic active zones (AZs) is a prerequisite for generating postsynaptic target cell type-specific differences in presynaptic vesicle release probability (Pv) and short-term plasticity, a characteristic feature of cortical pyramidal cells… read more here.
Keywords: mglur1 expressing; munc13; expressing interneurons; presynaptic active ... See more keywords