Efferent projections of CGRP/Calca‐expressing parabrachial neurons in mice
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25136
Abstract: The parabrachial nucleus (PB) is composed of glutamatergic neurons at the midbrain–hindbrain junction. These neurons form many subpopulations, one of which expresses Calca, which encodes the neuropeptide calcitonin gene‐related peptide (CGRP). This Calca‐expressing subpopulation has… read more here.
Keywords: calca; efferent projections; calca expressing; cgrp calca ... See more keywords
Uncovering the brain‐wide pattern of synaptic input to vasopressin‐expressing neurons in the paraventricular nucleus of the hypothalamus
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25476
Abstract: Arginine vasopressin (AVP) is a neuropeptide critical for the mammalian stress response and social behavior. AVP produced in the hypothalamus regulates water osmolality and vasoconstriction in the body, and in the brain, it regulates social… read more here.
Keywords: vasopressin; brain; expressing neurons; social behavior ... See more keywords
Nucleus Accumbens Tac1-Expressing Neurons Mediate Stress-Induced Anhedonia-like Behavior in Mice.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.108343
Abstract: Major depressive disorder (MDD) presents with two primary symptoms: depressed mood and anhedonia, which suggests that distinct neuronal circuits may regulate MDD. However, the underlying circuits of these individual symptoms linked to depression remain elusive.… read more here.
Keywords: like behavior; expressing neurons; stress; anhedonia like ... See more keywords
Tac1-Expressing Neurons in the Periaqueductal Gray Facilitate the Itch-Scratching Cycle via Descending Regulation
Sign Up to like & getrecommendations! Published in 2019 at "Neuron"
DOI: 10.1016/j.neuron.2018.11.010
Abstract: Uncontrollable itch-scratching cycles lead to serious skin damage in patients with chronic itch. However, the neural mechanism promoting the itch-scratching cycle remains elusive. Here, we report that tachykinin 1 (Tac1)-expressing glutamatergic neurons in the lateral… read more here.
Keywords: itch scratching; itch; scratching behavior; scratching cycle ... See more keywords
A cell-type-specific circuit of somatostatin neurons in the habenula encodes antidepressant action in male mice
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-58591-y
Abstract: Major depression is characterized by an array of negative experiences, including hopelessness and anhedonia. We hypothesize that inhibition of negative experiences or aversion may generate antidepressant action. To directly test this hypothesis, we perform multimodal… read more here.
Keywords: circuit; expressing neurons; male mice; antidepressant action ... See more keywords
The non-receptor tyrosine kinase Pyk2 modulates acute locomotor effects of cocaine in D1 receptor-expressing neurons of the nucleus accumbens
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-63426-5
Abstract: The striatum is critical for cocaine-induced locomotor responses. Although the role of D1 receptor-expressing neurons is established, underlying molecular pathways are not fully understood. We studied the role of Pyk2, a non-receptor, calcium-dependent protein-tyrosine kinase.… read more here.
Keywords: locomotor; pyk2; tyrosine; expressing neurons ... See more keywords
719 - Modulating Nav1.8-expressing neurons offers promising direction to address symptoms of atopic dermatitis
Sign Up to like & getrecommendations! Published in 2024 at "British Journal of Dermatology"
DOI: 10.1093/bjd/ljae266.092
Abstract: Atopic dermatitis (AD) is an inflammatory skin condition characterized by eczematous lesions, itch and pain. The inflammation and itch associated with AD are caused in part by dysregulation of neuroimmune circuits. Understanding these circuits is… read more here.
Keywords: mice; control; expressing neurons; pain ... See more keywords
Electrophysiological characteristics of leptin receptor-expressing neurons in the dorsomedial hypothalamus
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5794371
Abstract: The adipocyte-derived hormone leptin acts at leptin receptor (LepR)-expressing neurons in the brain to regulate metabolic and cardiovascular functions. LepR neurons in the dorsomedial hypothalamus (DMH) are required for leptin-induced feeding suppression, regulate brown adipose… read more here.
Keywords: lepr neurons; leptin excited; leptin receptor; expressing neurons ... See more keywords
Analgesia by deletion of spinal neurokinin 1 receptor expressing neurons using a bioengineered substance P-Pseudomonas exotoxin conjugate
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Pain"
DOI: 10.1177/1744806917727657
Abstract: Cell deletion approaches to pain directed at either the primary nociceptive afferents or second-order neurons are highly effective analgesic manipulations. Second-order spinal neurons expressing the neurokinin 1 (NK1) receptor are required for the perception of… read more here.
Keywords: pseudomonas exotoxin; nk1 receptor; deletion; expressing neurons ... See more keywords
Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization
Sign Up to like & getrecommendations! Published in 2018 at "BMC Neuroscience"
DOI: 10.1186/s12868-018-0469-1
Abstract: BackgroundFoxP transcription factors play crucial roles for the development and function of vertebrate brains. In humans the neurally expressed FOXPs, FOXP1, FOXP2, and FOXP4 are implicated in cognition, including language. Neural FoxP expression is specific… read more here.
Keywords: identification neurotransmitter; neuron populations; amfoxp; expressing neurons ... See more keywords
Morphological Analysis of the Axonal Projections of EGFP-Labeled Esr1-Expressing Neurons in Transgenic Female Medaka
Sign Up to like & getrecommendations! Published in 2018 at "Endocrinology"
DOI: 10.1210/en.2017-00873
Abstract: Some hypothalamic neurons expressing estrogen receptor α (Esr1) are thought to transmit a gonadal estrogen feedback signal to gonadotropin-releasing hormone 1 (GnRH1) neurons, which is the final common pathway for feedback regulation of reproductive functions.… read more here.
Keywords: gnrh1 neurons; esr1 neurons; esr1 expressing; estrogen ... See more keywords