RUNX‐mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins
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DOI: 10.1002/jcb.26443
Abstract: RUNX gene over‐expression inhibits growth of primary cells but transforms cells with tumor suppressor defects, consistent with reported associations with tumor progression. In contrast, chromosomal translocations involving RUNX1 are detectable in utero, suggesting an initiating… read more here.
Keywords: expressing runx1; cells expressing; senescence; runx1 fusion ... See more keywords