Analgesic Tolerance Development during Repetitive Electric Stimulations Is Associated with Changes in the Expression of Activated Microglia in Rats with Osteoarthritis
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DOI: 10.3390/biomedicines8120575
Abstract: Electric stimulation is used for managing osteoarthritic (OA) pain; however, little is known about the development of analgesic tolerance during repeated stimulations and the relation of spinal microglia with OA pain. We investigated the changes… read more here.
Keywords: tolerance; knee joint; activated microglia; expression activated ... See more keywords