Fas (CD95) expression in adipocytes contributes to diet‐induced obesity
Sign Up to like & getrecommendations! Published in 2024 at "Obesity"
DOI: 10.1002/oby.24092
Abstract: Induction of browning in white adipose tissue (WAT) increases energy expenditure and may be an attractive target for the treatment of obesity. Since activation of Fas (CD95) induces pathways known to blunt expression of uncoupling… read more here.
Keywords: fas cd95; obesity; expression adipocytes; cd95 expression ... See more keywords
Glucose availability regulates nicotinamide N-methyltransferase expression in adipocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117474
Abstract: BACKGROUND/OBJECTIVES Nicotinamide N-methyltransferase (NNMT) is a novel regulator of energy homeostasis in adipocytes. NNMT expression in adipose tissue is increased in obesity and diabetes. Knockdown of NNMT prevents mice from developing diet-induced obesity, which is… read more here.
Keywords: availability regulates; nnmt expression; expression; glucose availability ... See more keywords
Bidirectional manipulation of gene expression in adipocytes using CRISPRa and siRNA
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2017.07.001
Abstract: Objective Functional investigation of novel gene/protein targets associated with adipocyte differentiation or function heavily relies on efficient and accessible tools to manipulate gene expression in adipocytes in vitro. Recent advances in gene-editing technologies such as… read more here.
Keywords: gene expression; expression; gene; manipulation ... See more keywords