Glucose availability regulates nicotinamide N-methyltransferase expression in adipocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117474
Abstract: BACKGROUND/OBJECTIVES Nicotinamide N-methyltransferase (NNMT) is a novel regulator of energy homeostasis in adipocytes. NNMT expression in adipose tissue is increased in obesity and diabetes. Knockdown of NNMT prevents mice from developing diet-induced obesity, which is… read more here.
Keywords: availability regulates; nnmt expression; expression; glucose availability ... See more keywords
Bidirectional manipulation of gene expression in adipocytes using CRISPRa and siRNA
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2017.07.001
Abstract: Objective Functional investigation of novel gene/protein targets associated with adipocyte differentiation or function heavily relies on efficient and accessible tools to manipulate gene expression in adipocytes in vitro. Recent advances in gene-editing technologies such as… read more here.
Keywords: gene expression; expression; gene; manipulation ... See more keywords