Outcomes in patients with early‐stage breast cancer who underwent a 21‐gene expression assay
Sign Up to like & getrecommendations! Published in 2017 at "Cancer"
DOI: 10.1002/cncr.30618
Abstract: Invasive disease‐free survival (IDFS) rates are excellent in patients with breast cancer (BC) with hormone receptor‐positive (HR+), human epidermal growth factor receptor 2‐negative (HER2‐), axillary lymph node‐negative (LN‐) tumors with a 21‐gene expression assay recurrence… read more here.
Keywords: cancer; expression assay; gene expression; breast cancer ... See more keywords
Use of adjuvant chemotherapy in hormone receptor-positive breast cancer patients with or without the 21-gene expression assay
Sign Up to like & getrecommendations! Published in 2018 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-018-4740-z
Abstract: PurposeWe assessed the use of chemotherapy in breast cancer patients to investigate the factors that changed trends in chemotherapy following the adoption of the 21-gene expression assay in tumor genomic profiling.MethodsOur study used 2033 patients… read more here.
Keywords: chemotherapy; use; gene expression; expression assay ... See more keywords
PD-L1 immuno-expression assay in thymomas: Study of 84 cases and review of literature.
Sign Up to like & getrecommendations! Published in 2018 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2018.03.012
Abstract: BACKGROUND AND AIMS Programmed death ligand 1 (PD-L1), an immune check point inhibitor, is known to be expressed in several malignancies and is being considered as a prognostic factor and a potential immunotherapeutic target. The… read more here.
Keywords: literature; study; expression; expression assay ... See more keywords
Development of a Gene Expression Assay for the Diagnosis of Mycobacterium bovis Infection in African Lions (Panthera leo)
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DOI: 10.1111/tbed.12436
Abstract: Mycobacterium bovis infection, the cause of bovine tuberculosis (BTB), is endemic in wildlife in the Kruger National Park (KNP), South Africa. In lions, a high infection prevalence and BTB mortalities have been documented in the… read more here.
Keywords: expression assay; infection; bovis; gene expression ... See more keywords
Human CTL-based functional analysis shows the reliability of a munc13-4 protein expression assay for FHL3 diagnosis.
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2017-10-812503
Abstract: Familial hemophagocytic lymphohistiocytosis (FHL) is the major form of hereditary hemophagocytic lymphohistiocytosis (HLH); as such, it requires prompt and accurate diagnosis. We previously reported that FHL type 3 (FHL3) can be rapidly screened by detecting… read more here.
Keywords: diagnosis; expression; expression assay; munc13 protein ... See more keywords
The clinical utility of the 90-gene expression assay on diagnosis and management in patients with cancer of unknown or unclear primary.
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DOI: 10.1200/jco.2024.42.16_suppl.e15172
Abstract: e15172 Background: The diagnosis and management of patients with cancer of unknown or unclear primary present significant clinical hurdles, often culminating in unfavorable outcomes. A randomized phase III trial (CUP001) has demonstrated that site-specific treatment… read more here.
Keywords: cancer unknown; cancer; gene expression; patients cancer ... See more keywords
Endocrine Therapy Response and 21-Gene Expression Assay for Therapy Guidance in HR+/HER2– Early Breast Cancer
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DOI: 10.1200/jco.21.02759
Abstract: PURPOSE To our knowledge, WSG-ADAPT-HR+/HER2– (ClinicalTrials.gov identifier: NCT01779206; n = 5,625 registered) is the first trial combining the 21-gene expression assay (recurrence score [RS]) and response to 3-week preoperative endocrine therapy (ET) to guide systemic… read more here.
Keywords: early breast; expression assay; therapy; gene expression ... See more keywords