ATM expression is attenuated by promoter hypermethylation in human ovarian endometriotic stromal cells.
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DOI: 10.1093/molehr/gaz016
Abstract: A number of genes involved in the pathogenesis of endometriosis are silenced by the hypermethylation of their promoter regions. We assessed the effect and mechanism of the DNA demethylating agent 5-aza-2'-deoxycytidine (5-aza-dC) (10 μM) on the… read more here.
Keywords: hypermethylation; stromal cells; aza; expression ... See more keywords