Physalin B reduces Aβ secretion by downregulating the expression of BACE1 via the activation of FoxO1 and the inhibition of STAT3 phosphorylation
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DOI: 10.1016/s1875-5364(21)60090-0
Abstract: Physalin B (PB), one of the major active steroidal constituents of Solanaceae Physalis plants, has a wide variety of biological activities. We found that PB significantly downregulated β-amyloid (Aβ) secretions in N2a/APPsw cells. However, the… read more here.
Keywords: expression; expression bace1; phosphorylation; secretion ... See more keywords