Metabolically-targeted dCas9 expression in bacteria
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1248
Abstract: Abstract The ability to restrict gene expression to a relevant bacterial species in a complex microbiome is an unsolved problem. In the context of the human microbiome, one desirable target metabolic activity are glucuronide-utilization enzymes… read more here.
Keywords: targeted dcas9; expression bacteria; expression; metabolically targeted ... See more keywords
Light-regulated gene expression in Bacteria: Fundamentals, advances, and perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.1029403
Abstract: Numerous photoreceptors and genetic circuits emerged over the past two decades and now enable the light-dependent i.e., optogenetic, regulation of gene expression in bacteria. Prompted by light cues in the near-ultraviolet to near-infrared region of… read more here.
Keywords: light regulated; regulated gene; expression bacteria; expression ... See more keywords
Modelling hCDKL5 Heterologous Expression in Bacteria
Sign Up to like & getrecommendations! Published in 2021 at "Metabolites"
DOI: 10.3390/metabo11080491
Abstract: hCDKL5 refers to the human cyclin-dependent kinase like 5 that is primarily expressed in the brain. Mutations in its coding sequence are often causative of hCDKL5 deficiency disorder, a devastating neurodevelopmental disorder currently lacking a… read more here.
Keywords: production; hcdkl5 heterologous; modelling hcdkl5; heterologous expression ... See more keywords