PROMOTER CHOICE: THE IDEAL PROMOTER TO DRIVE CHIMERIC ANTIGEN RECEPTOR (CAR) EXPRESSION IN NK CELLS
Sign Up to like & getrecommendations! Published in 2021 at "Hematology, Transfusion and Cell Therapy"
DOI: 10.1016/j.htct.2021.10.455
Abstract: Aims Natural Killer (NK) cells have gained much recent attention as a promising alternative platform for CAR engineering owing to their unique biological attributes, their specialized cytotoxicity against tumors, their safety profile, and their potential… read more here.
Keywords: expression; promoter drive; expression cells; cd19 ... See more keywords
Elevated IL18 levels in Nasopharyngeal carcinoma induced PD-1 expression on NK cells in TILS leading to poor prognosis.
Sign Up to like & getrecommendations! Published in 2020 at "Oral oncology"
DOI: 10.1016/j.oraloncology.2020.104616
Abstract: OBJECTIVES Characterisation of tumor-infiltrating lymphocytes (TILS) population for cancer prognostication has enabled deeper understanding of tumor immune interactions in cancer immunology. We aim to examine the significance of both the density and functional status of… read more here.
Keywords: expression cells; npc patients; elevated il18; induced expression ... See more keywords
Phenotypic and functional characterization of natural killer cells in rheumatoid arthritis-regulation with interleukin-15
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-62654-z
Abstract: Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial inflammation and joint destruction. Previous studies have shown that natural killer (NK) cells may play an important role in the pathogenesis of RA. Interleukin (IL)-15,… read more here.
Keywords: expression cells; natural killer; cells patients; expression ... See more keywords
Reply to Lombardi et al
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DOI: 10.1093/ofid/ofad084
Abstract: TO THE EDITOR—We thank Lombardi and colleagues for their thoughtful observations about our case and appreciate the opportunity to respond. We fully agree with the authors that the high PD-1 expression on T cells in… read more here.
Keywords: expression cells; expression; ici treatment; case ... See more keywords
Dysfunctional role of elevated TIGIT expression on T cells in oral squmaous cell carcinoma patients.
Sign Up to like & getrecommendations! Published in 2020 at "Oral diseases"
DOI: 10.1111/odi.13703
Abstract: OBJECTIVE This study was aimed to analyze the role of T-cell immunoreceptor with immunoglobulin and tyrosine-based inhibitory motif domains (TIGIT) expression on T cells in patients with oral squamous cell carcinoma (OSCC). MATERIALS AND METHODS… read more here.
Keywords: expression cells; tigit expression; cell carcinoma; oscc patients ... See more keywords
The Trend of TIM3 Expression on T Cells in Patients With Nontuberculous Mycobacterial Lung Disease: From Immune Cell Dysfunction to Clinical Severity
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.738056
Abstract: Background The incidence of nontuberculous mycobacterial lung disease (NTM-LD) is increasing worldwide. Immune exhaustion has been reported in NTM-LD, but T-cell immunoglobulin and mucin domain-containing protein 3 (TIM3), a co-inhibitory receptor on T cells, has… read more here.
Keywords: expression; cd8 cells; expression cells; disease ... See more keywords
Inversed Ratio of CD39/CD73 Expression on γδ T Cells in HIV Versus Healthy Controls Correlates With Immune Activation and Disease Progression
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.867167
Abstract: Background γδ T cells are unconventional T cells that have been demonstrated to be crucial for the pathogenesis and potentially for the cure of HIV-1 infection. The ectonucleotidase CD39 is part of the purinergic pathway… read more here.
Keywords: cd39 cd73; cd39; expression cells; cd73 expression ... See more keywords
Imaging Changes and Immune-Checkpoint Expression on T Cells in Bronchoalveolar Lavage Fluid from Patients with Pulmonary Sarcoidosis
Sign Up to like & getrecommendations! Published in 2021 at "Biomedicines"
DOI: 10.3390/biomedicines9091231
Abstract: Sarcoidosis is a systemic, granulomatous disease caused by unknown immunological abnormalities. The organs most vulnerable to sarcoidosis are the lungs. Patients often resolve spontaneously, but the lungs can also be severely affected. Although details regarding… read more here.
Keywords: immune checkpoint; expression cells; sarcoidosis; cells bronchoalveolar ... See more keywords