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Published in 2018 at "Purinergic Signalling"
DOI: 10.1007/s11302-018-9620-9
Abstract: Purinergic P2X receptors, when activated under pathological conditions, participate in induction of the inflammatory response and/or cell death. Both neuroinflammation and neurodegeneration represent hallmarks of multiple sclerosis (MS), an autoimmune disease of the central nervous…
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Keywords:
administration;
expression claudin;
eae;
p2x7 receptor ... See more keywords
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Published in 2018 at "Molecular Psychiatry"
DOI: 10.1038/mp.2017.156
Abstract: Schizophrenia is a neurodevelopmental disorder that affects up to 1% of the general population. Various genes show associations with schizophrenia and a very weak nominal association with the tight junction protein, claudin-5, has previously been…
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Keywords:
schizophrenia;
modifying factor;
claudin;
expression claudin ... See more keywords
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Published in 2017 at "BMC Gastroenterology"
DOI: 10.1186/s12876-017-0590-0
Abstract: BackgroundClaudins are a family of integral membrane proteins and are components of tight junctions (TJs). Many TJ proteins are known to tighten the cell structure and maintain a barrier. Claudin-2 forms gated paracellular channels and…
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Keywords:
receptors vdr;
precancerous lesions;
expression claudin;
expression ... See more keywords
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Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.4038
Abstract: 4038Background: Claudin 18.2 (CLDN18.2), a gastric mucosa tight junction protein, is aberrantly expressed in various cancers. In the FAST Phase 2 trial (NCT01630083), IMAB362, an anti-CLDN18.2 mono...
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Keywords:
claudin;
claudin her2;
expression claudin;
junction ... See more keywords