Articles with "expression claudin" as a keyword



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Administration of an antagonist of P2X7 receptor to EAE rats prevents a decrease of expression of claudin-5 in cerebral capillaries

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Published in 2018 at "Purinergic Signalling"

DOI: 10.1007/s11302-018-9620-9

Abstract: Purinergic P2X receptors, when activated under pathological conditions, participate in induction of the inflammatory response and/or cell death. Both neuroinflammation and neurodegeneration represent hallmarks of multiple sclerosis (MS), an autoimmune disease of the central nervous… read more here.

Keywords: administration; expression claudin; eae; p2x7 receptor ... See more keywords
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Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia

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Published in 2018 at "Molecular Psychiatry"

DOI: 10.1038/mp.2017.156

Abstract: Schizophrenia is a neurodevelopmental disorder that affects up to 1% of the general population. Various genes show associations with schizophrenia and a very weak nominal association with the tight junction protein, claudin-5, has previously been… read more here.

Keywords: schizophrenia; modifying factor; claudin; expression claudin ... See more keywords
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High expression of Claudin-2 in esophageal carcinoma and precancerous lesions is significantly associated with the bile salt receptors VDR and TGR5

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Published in 2017 at "BMC Gastroenterology"

DOI: 10.1186/s12876-017-0590-0

Abstract: BackgroundClaudins are a family of integral membrane proteins and are components of tight junctions (TJs). Many TJ proteins are known to tighten the cell structure and maintain a barrier. Claudin-2 forms gated paracellular channels and… read more here.

Keywords: receptors vdr; precancerous lesions; expression claudin; expression ... See more keywords
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Expression of Claudin 18.2 and HER2 in gastric, gastroesophageal junction, and esophageal cancers: Results from the FAST study.

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Published in 2017 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2017.35.15_suppl.4038

Abstract: 4038Background: Claudin 18.2 (CLDN18.2), a gastric mucosa tight junction protein, is aberrantly expressed in various cancers. In the FAST Phase 2 trial (NCT01630083), IMAB362, an anti-CLDN18.2 mono... read more here.

Keywords: claudin; claudin her2; expression claudin; junction ... See more keywords