Expression of the CXCR4 and CXCR7 in renal cancers; can "the orphan receptor" predict the mortality?
Sign Up to like & getrecommendations! Published in 2021 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2021.151829
Abstract: CXCR4 and CXCR7 are chemokine receptors that bind with chemokine CXCL12 and influence various physiological and pathological processes. In renal cell carcinoma, their expression has been mostly associated with tumour aggressiveness. However, there are some… read more here.
Keywords: cxcr4 cxcr7; mortality; expression; expression cxcr4 ... See more keywords
PO-393 Notch3 and CXCR4 cross-signalling sustains acute T-cell leukaemia progression
Sign Up to like & getrecommendations! Published in 2018 at "ESMO Open"
DOI: 10.1136/esmoopen-2018-eacr25.905
Abstract: Introduction Acute T-cell lymphoblastic leukaemia (T-ALL) is a childhood cancer, characterised by infiltration of immature T-cells in bone marrow. Notch hyperactivation is a major driver of T-ALL development where CXCL12/CXCR4 axis plays an important role… read more here.
Keywords: notch3 cxcr4; acute cell; expression cxcr4; cell ... See more keywords