Regulatory variants in a novel distal enhancer regulate the expression of CYP3A4 and CYP3A5
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Science"
DOI: 10.1111/cts.13398
Abstract: The cytochrome P450 3As (CYP3As) are abundantly expressed in the liver and metabolize many commonly prescribed medications. Their expression is highly variable between individuals with little known genetic cause. Despite extensive investigation, cisâacting genetic elements… read more here.
Keywords: regulatory variants; expression; cyp3a4 cyp3a5; cyp3a4 ... See more keywords