Expression dynamics of HAND1/2 in in vitro human cardiomyocyte differentiation
Sign Up to like & getrecommendations! Published in 2021 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2021.06.014
Abstract: Summary Hand1 and Hand2 are transcriptional factors, and knockout mice of these genes show left and right ventricular hypoplasia, respectively. However, their function and expression in human cardiogenesis are not well studied. To delineate their… read more here.
Keywords: expression dynamics; cms; dynamics hand1; expression ... See more keywords
De novo full length transcriptome analysis of Arachis glabrata provides insights into gene expression dynamics in response to biotic and abiotic stresses.
Sign Up to like & getrecommendations! Published in 2021 at "Genomics"
DOI: 10.1016/j.ygeno.2021.03.030
Abstract: The perennial ornamental peanut Arachis glabrata represents one of the most adaptable wild Arachis species. This study used PacBio combined with BGISEQ-500 RNA-seq technology to study the transcriptome and gene expression dynamics of A. glabrata.… read more here.
Keywords: arachis; expression dynamics; glabrata; gene expression ... See more keywords
Alignment of single-cell trajectories to compare cellular expression dynamics
Sign Up to like & getrecommendations! Published in 2018 at "Nature Methods"
DOI: 10.1038/nmeth.4628
Abstract: Single-cell RNA sequencing and high-dimensional cytometry can be used to generate detailed trajectories of dynamic biological processes such as differentiation or development. Here we present cellAlign, a quantitative framework for comparing expression dynamics within and… read more here.
Keywords: single cell; alignment single; expression dynamics; cell trajectories ... See more keywords
Hormonal regulation of microRNA expression dynamics in the gut of the yellow fever mosquito Aedes aegypti.
Sign Up to like & getrecommendations! Published in 2020 at "RNA biology"
DOI: 10.1080/15476286.2020.1864181
Abstract: The yellow fever mosquito Aedes aegypti is an obligatory blood feeder and a major arboviral disease vector, evoking severe public health concerns worldwide. In adult female mosquitoes, the gut is critical for blood digestion and… read more here.
Keywords: mosquito aedes; yellow fever; expression dynamics; expression ... See more keywords
The mitoXplorer 2.0 update: integrating and interpreting mitochondrial expression dynamics within a cellular context
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac306
Abstract: Mitochondria are subcellular organelles present in almost all eukaryotic cells, which play a central role in cellular metabolism. Different tissues, health and age conditions are characterised by a difference in mitochondrial structure and composition. The… read more here.
Keywords: expression dynamics; mitoxplorer; cellular context; mitoxplorer update ... See more keywords
mitoXplorer, a visual data mining platform to systematically analyze and visualize mitochondrial expression dynamics and mutations
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz1128
Abstract: Abstract Mitochondria participate in metabolism and signaling. They adapt to the requirements of various cell types. Publicly available expression data permit to study expression dynamics of genes with mitochondrial function (mito-genes) in various cell types,… read more here.
Keywords: data mining; expression dynamics; mitochondrial expression; mining platform ... See more keywords
The Expression Dynamics of piRNAs Derived From Male Germline piRNA Clusters and Retrotransposons
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.868746
Abstract: In mammals, germ cells produce a class of small regulatory RNAs called PIWI-interacting RNAs or piRNAs, which are 25–32 nucleotides in length. The profile of testicular piRNAs changes during development. The piRNAs detected in fetal… read more here.
Keywords: type pirnas; expression dynamics; pirna clusters; germ cells ... See more keywords
Expression Dynamics of CA IX Epitope in Cancer Cells under Intermittent Hypoxia Correlates with Extracellular pH Drop and Cell Killing by Ureido-Sulfonamide CA IX Inhibitors
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24054595
Abstract: Carbonic anhydrase IX (CA IX) is a membrane-bound CA isozyme over-expressed in many hypoxic tumor cells, where it ensures pH homeostasis and has been implicated in tumor survival, metastasis and resistance to chemotherapy and radiotherapy.… read more here.
Keywords: tumor; expression dynamics; cancer cells; intermittent hypoxia ... See more keywords
Fine-tuning of gene expression dynamics by the Set2-Rpd3S pathway
Sign Up to like & getrecommendations! Published in 2017 at "BMB Reports"
DOI: 10.5483/bmbrep.2017.50.4.049
Abstract: RNA polymerase II-interacting the Set2 methyltransferase co-transcriptionally methylates histone H3 at lysine 36 within the body of genes. This modification facilitates histone deacetylation by Rpd3S HDAC in 3′ transcribed regions to suppress cryptic initiation and… read more here.
Keywords: set2 rpd3s; fine tuning; expression dynamics; pathway ... See more keywords
Cis-regulatory variants affect gene expression dynamics in yeast
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.68469
Abstract: Evolution of cis-regulatory sequences depends on how they affect gene expression and motivates both the identification and prediction of cis-regulatory variants responsible for expression differences within and between species. While much progress has been made… read more here.
Keywords: expression; regulatory variants; gene expression; expression dynamics ... See more keywords