FAST-1 antisense RNA epigenetically alters FXN expression
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-35639-2
Abstract: Friedreich ataxia (FRDA) is a multisystem genetic disorder caused by GAA repeat expansion mutations within the FXN gene, resulting in heterochromatin formation and deficiency of frataxin protein. Elevated levels of the FXN antisense transcript (FAST-1)… read more here.
Keywords: fast frda; expression fast; expression; fxn expression ... See more keywords