LIN28 expression and function in medulloblastoma
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30946
Abstract: Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Current treatment modalities are not completely effective and can lead to severe neurological and cognitive adverse effects. In addition to urgently needing better treatment approaches,… read more here.
Keywords: function medulloblastoma; lin28 expression; expression function; expression ... See more keywords
Impaired expression and function of TLR8 in chronic HBV infection and its association with treatment responses during peg-IFN-α-2a antiviral therapy.
Sign Up to like & getrecommendations! Published in 2017 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2016.12.006
Abstract: BACKGROUND AND AIM Toll-like receptor 8 (TLR8) plays an important role in controlling chronic viral infections. However, the role of TLR8 in chronic hepatitis B virus (HBV) infection is poorly understood. In this study, we aimed to… read more here.
Keywords: hbv infection; expression; therapy; expression function ... See more keywords
The expression and function of PAX3 in development and disease.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.04.087
Abstract: The PAX3 gene encodes a member of the PAX family of transcription factors that is characterized by a highly conserved paired box motif. The PAX3 protein is a transcription factor consisting of an N-terminal DNA… read more here.
Keywords: function pax3; expression function; development; pax3 ... See more keywords
Effect of Liver Disease on Hepatic Transporter Expression and Function.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2017.04.053
Abstract: Liver disease can alter the disposition of xenobiotics and endogenous substances. Regulatory agencies such as the Food and Drug Administration and the European Medicines Evaluation Agency recommend, if possible, studying the effect of liver disease… read more here.
Keywords: liver disease; expression function; effect liver; disease ... See more keywords
Identification, expression and function of myosin heavy chain family genes in Tribolium castaneum.
Sign Up to like & getrecommendations! Published in 2018 at "Genomics"
DOI: 10.1016/j.ygeno.2018.04.010
Abstract: Functions of myosin heavy chain (myosin) family genes are poorly understood in some insects. To address this, we determined the expression and function of myosin family genes in Tribolium castaneum. TcMyo15 is predominantly expressed in… read more here.
Keywords: heavy chain; family; myosin heavy; family genes ... See more keywords
Analysis of the expression, function, and evolution of miR-27 isoforms and their responses in metabolic processes.
Sign Up to like & getrecommendations! Published in 2018 at "Genomics"
DOI: 10.1016/j.ygeno.2018.08.004
Abstract: This study aimed to discuss the potential roles of isomiRs of miR-27 family in metabolisms associated with disease via analyses of their evolution, expression, and function. miR-27b-3p was relatively highly expressed in liver cancer samples… read more here.
Keywords: function evolution; mir; expression; analysis expression ... See more keywords
Bile duct ligation enhances AZT CNS toxicity partly by impairing the expression and function of BCRP in rat brain
Sign Up to like & getrecommendations! Published in 2019 at "Acta Pharmacologica Sinica"
DOI: 10.1038/s41401-019-0242-8
Abstract: Breast cancer resistance protein (BCRP) is one of ATP-binding cassette (ABC) transporters in brain microvessel endothelial cells that transport their substrates from brain to blood, thus limiting substrates to crossing into brain through blood–brain barrier.… read more here.
Keywords: bcrp; brain; expression function; bdl rats ... See more keywords
Expression and function of ATP-dependent potassium channels in zebrafish islet β-cells
Sign Up to like & getrecommendations! Published in 2017 at "Royal Society Open Science"
DOI: 10.1098/rsos.160808
Abstract: ATP-sensitive potassium channels (KATP channels) are critical nutrient sensors in many mammalian tissues. In the pancreas, KATP channels are essential for coupling glucose metabolism to insulin secretion. While orthologous genes for many components of metabolism–secretion… read more here.
Keywords: potassium channels; islet; zebrafish islet; islet cells ... See more keywords
The expression and function of galectins in skin physiology and pathology
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Dermatology"
DOI: 10.1111/exd.13512
Abstract: The galectin family comprises β‐galactoside–binding proteins widely expressed in many organisms. There are at least 16 family members, which can be classified into three groups based on their carbohydrate‐recognition domains. Pleiotropic functions of different galectins… read more here.
Keywords: galectins skin; pathology; physiology; cell ... See more keywords
Viperin catalyzes methionine oxidation to promote protein expression and function of helicases
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aax1031
Abstract: Methionine oxidation by viperin is critical for the expression and function of helicases. Helicases play pivotal roles in fundamental biological processes, and posttranslational modifications regulate the localization, function, and stability of helicases. Here, we report… read more here.
Keywords: oxidation; methionine oxidation; catalyzes methionine; function helicases ... See more keywords
Abstract 4369381: Regulation of Nav1.5 Channel Surface Expression and Function by Sorbs2 in Atrial Cardiomyocytes
Sign Up to like & getrecommendations! Published in 2025 at "Circulation"
DOI: 10.1161/circ.152.suppl_3.4369381
Abstract: Background: Voltage-gated Nav1.5 channel, encoded by SCN5A , is essential for initiation and propagation of action potentials (AP) in atria. Nav1.5 channelopathy is strongly associated with arrhythmogenesis, including atrial fibrillation. Sorbin and SH3 domain-containing protein… read more here.
Keywords: atrial cardiomyocytes; nav1 channel; sorbs2; expression function ... See more keywords