Effect of troxerutin on oxidative stress and expression of genes regulating mitochondrial biogenesis in doxorubicin-induced myocardial injury in rats
Sign Up to like & getrecommendations! Published in 2020 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-020-01818-0
Abstract: Because of limitation of doxorubicin (DOX) clinical application in chemotherapy due to its cardiotoxicity, finding new strategies to reduce DOX challenge and improve patients’ outcomes is crucial. Due to positive cardiovascular impacts of troxerutin (TXR),… read more here.
Keywords: biogenesis; expression genes; effect; expression ... See more keywords
Expression of genes that encode cellular oxidant/antioxidant systems are affected by heat stress
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology Reports"
DOI: 10.1007/s11033-018-4173-0
Abstract: Heat stress causes critical molecular dysfunction that affects productivity in chickens. Thus, the purpose of this study was to evaluate the effect of heat stress (HS) on the expression of select genes in the oxidation/antioxidation… read more here.
Keywords: expression genes; heat stress; expression; stress expression ... See more keywords
Beauvericin alters the expression of genes coding for key proteins of the mitochondrial chain in ovine cumulus-oocyte complexes.
Sign Up to like & getrecommendations! Published in 2020 at "Mycotoxin research"
DOI: 10.1007/s12550-020-00409-5
Abstract: Beauvericin (BEA) is a member of the enniatin family of mycotoxins which has received increasing interest because of frequent occurrence in food and feed. By its ionophoric properties, BEA is able to alter membrane ion… read more here.
Keywords: cumulus cells; expression genes; proteins mitochondrial; genes coding ... See more keywords
Crohn's Colitis: Development of a multiplex gene expression assay comparing mRNA levels of susceptibility genes.
Sign Up to like & getrecommendations! Published in 2017 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2017.02.004
Abstract: Crohn's disease (CD) is a multifactorial immunologically mediated disease. In this study we explored, for the first time, the efficacy of the Multiplex Gene Assay technology for detecting mRNA expression profile of 24 selected CD… read more here.
Keywords: multiplex gene; response; expression genes; expression ... See more keywords
Differential expression of genes in C. elegans reveals transcriptional responses to indirect-acting xenobiotic compounds and insensitivity to 2,3,7,8-tetrachlorodibenzodioxin.
Sign Up to like & getrecommendations! Published in 2022 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2022.113344
Abstract: Caenorhabditis elegans is a well-established model organism for toxicity testing of chemical substances. We recently demonstrated its potential for bioanalysis of the toxic potency of chemical contaminants in water. While many detoxification genes are homologues… read more here.
Keywords: differential expression; expression; expression genes; transcriptional responses ... See more keywords
Organochloride pesticides modulated gut microbiota and influenced bile acid metabolism in mice.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental pollution"
DOI: 10.1016/j.envpol.2017.03.068
Abstract: Organochlorine pesticides (OCPs) can persistently accumulate in body and threaten human health. Bile acids and intestinal microbial metabolism have emerged as important signaling molecules in the host. However, knowledge on which intestinal microbiota and bile… read more here.
Keywords: bile acids; microbiota; metabolism; expression genes ... See more keywords
Altered expression of genes involved in programmed cell death in primary cultured rat cerebellar granule cells acutely challenged with tetrabromobisphenol A
Sign Up to like & getrecommendations! Published in 2017 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2017.09.014
Abstract: HighlightsThe viability of primary CGC continuously declines after acute challenge with TBBPA.Genes related to programmed necrosis are not induced in CGC by TBBPA.Early suppression by TBBPA of the autophagy and apoptotic genes in CGC.Delayed activation… read more here.
Keywords: genes involved; mgr tbbpa; expression genes; pro apoptotic ... See more keywords
Maternal undernutrition during pregnancy alters the epigenetic landscape and the expression of endothelial function genes in male progeny.
Sign Up to like & getrecommendations! Published in 2019 at "Nutrition research"
DOI: 10.1016/j.nutres.2018.10.005
Abstract: Recent studies point to the important role of in utero malnutrition in gene programming and in the development of vascular diseases. We hypothesize that maternal undernutrition affects vascular function in the offspring by promoting epigenetic… read more here.
Keywords: maternal undernutrition; expression genes; expression; mice ... See more keywords
Cpe1786/IscR of Clostridium perfringens represses expression of genes involved in Fe-S cluster biogenesis.
Sign Up to like & getrecommendations! Published in 2017 at "Research in microbiology"
DOI: 10.1016/j.resmic.2016.03.002
Abstract: Cpe1786 of Clostridium perfringens is an Rrf2-type regulator containing the three-cysteine residues coordinating a Fe-S in IscR, the repressor controlling Fe-S homeostasis in enterobacteria. The cpe1786 gene formed an operon with iscSU involved in Fe-S… read more here.
Keywords: cpe1786; iscr; clostridium perfringens; expression genes ... See more keywords
Differential expression of genes involved in the response of Prunus spp. rootstocks under soil flooding
Sign Up to like & getrecommendations! Published in 2020 at "Scientia Horticulturae"
DOI: 10.1016/j.scienta.2019.109038
Abstract: Abstract The State of Rio Grande do Sul is used to produce the largest volume of peaches in Brazil. However, productivity in the state is lower than elsewhere in the country. One of the challenges… read more here.
Keywords: differential expression; response; expression genes; peach ... See more keywords
Lung expression of genes putatively involved in SARS-CoV-2 infection is modulated in cis by germline variants
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Human Genetics"
DOI: 10.1038/s41431-021-00831-y
Abstract: Germline variants in genes involved in SARS-CoV-2 cell entry and in host innate immune responses to viruses may influence the susceptibility to infection. This study used whole-genome analyses of lung tissue to identify polymorphisms acting… read more here.
Keywords: involved sars; expression genes; infection; expression ... See more keywords