N‐glycosylation and expression in human tissues of the orphan GPR61 receptor
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12339
Abstract: A number of members of the G protein‐coupled receptor class of cell surface receptors are ‘orphans’ with no known endogenous ligand. One of these orphan receptors is GPR61; there are little data about its expression… read more here.
Keywords: gpr61; expression human; glycosylation; expression ... See more keywords
Characterization of Fragile X Mental Retardation Protein expression in human nociceptors and their axonal projections to the spinal dorsal horn
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25463
Abstract: Fragile X Mental Retardation Protein (FMRP) regulates activity‐dependent RNA localization and local translation to modulate synaptic plasticity throughout the central nervous system. Mutations in the FMR1 gene that hinder or ablate FMRP function cause Fragile… read more here.
Keywords: fragile mental; retardation protein; mental retardation; fmrp ... See more keywords
Akt‐independent effects of triciribine on ACE2 expression in human lung epithelial cells: Potential benefits in restricting SARS‐CoV2 infection
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30343
Abstract: The severe acute respiratory syndrome coronavirus 2 that causes coronavirus disease 2019 (COVID‐19) binds to the angiotensin‐converting enzyme 2 (ACE2) to gain cellular entry. Akt inhibitor triciribine (TCBN) has demonstrated promising results in promoting recovery… read more here.
Keywords: epithelial cells; lung epithelial; ace2 expression; expression human ... See more keywords
Changes in Gene Expression in Human Epithelial and Mast Cells in Response to Vesicles from Klebsiella pneumonia ATCC 13883
Sign Up to like & getrecommendations! Published in 2018 at "Indian Journal of Microbiology"
DOI: 10.1007/s12088-018-0774-5
Abstract: AbstractWe investigated alterations in the expression of immune-related genes in epithelial cells and mast cells treated with outer membrane vesicles (OMVs) derived from Klebsiella pneumoniae (KpOMVs). Previous studies have shown that OMVs contain substances that… read more here.
Keywords: response; mast cells; expression human; gene expression ... See more keywords
IFN-β reduces NRP-1 expression on human cord blood monocytes and inhibits VEGF-induced chemotaxis.
Sign Up to like & getrecommendations! Published in 2021 at "Cytokine"
DOI: 10.1016/j.cyto.2021.155519
Abstract: Type I interferons (IFNs) inhibit angiogenesis, the sprouting of new blood vessels, during tissue development, remodeling, and tumor growth. One of the major targets type I IFNs inhibit are circulating monocytes, which promote vascular development… read more here.
Keywords: vegf; ifn; expression human; nrp expression ... See more keywords
Feasibility of the functional expression of the human organic anion transporting polypeptide 1B1 (OATP1B1) and its genetic variant 521T/C in the mouse liver
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2016.09.012
Abstract: &NA; The objective of this study was to examine the feasibility of functional expression of the human organic anion transporting polypeptide 1B1 (hOATP1B1) forms in the liver of the mouse. After the mouse received the… read more here.
Keywords: expression human; feasibility functional; liver; expression ... See more keywords
Characterization of the temporal, cell-specific and interferon-inducible patterns of indoleamine 2,3 dioxygenase 1 (IDO1) expression in the human placenta across gestation.
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DOI: 10.1016/j.placenta.2021.09.008
Abstract: INTRODUCTION The human placenta performs multiple functions necessary for successful pregnancy, but the metabolic pathways and molecular mechanisms responsible for regulating placental development and functions remain incompletely understood. Catabolism of the essential amino acid tryptophan… read more here.
Keywords: expression human; human placenta; ido1 expression; expression ... See more keywords
1,2-Dichloropropane induces γ-H2AX expression in human cholangiocytes only in the presence of macrophages.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2021.06.009
Abstract: Recent epidemiological studies reported cases of cholangiocarcinoma in workers exposed to 1,2-dichloropropane (1,2-DCP) in an offset proof printing factory in Japan. The present study investigated the effects of 1,2-DCP on the expression of histone family… read more here.
Keywords: induces h2ax; dichloropropane induces; expression human; expression ... See more keywords
Gefitinib Inhibits Rifampicin-Induced CYP3A4 Gene Expression in Human Hepatocytes
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DOI: 10.1021/acsomega.2c03270
Abstract: During multidrug combination chemotherapy, activation of the nuclear receptor and the transcription factor human pregnane xenobiotic receptor (hPXR) has been shown to play a role in the development of chemoresistance. Mechanistically, this could occur due… read more here.
Keywords: hpxr; expression human; gene expression; cyp3a4 gene ... See more keywords
Obesity and Roux-en-Y gastric bypass drive changes in miR-31 and miR-215 expression in the human rectal mucosa
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DOI: 10.1038/s41366-021-01005-y
Abstract: Obesity increases colorectal cancer (CRC) risk. However, the effects of weight loss on CRC risk are unclear. Epigenetic mechanisms involving microRNAs that lead to dysregulated gene expression may mediate the effects of obesity and weight… read more here.
Keywords: rectal mucosa; weight loss; expression human; expression ... See more keywords
lncRNA FER1L4 is dysregulated in osteoarthritis and regulates IL-6 expression in human chondrocyte cells
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DOI: 10.1038/s41598-021-92474-8
Abstract: Osteoarthritis (OA) is the most prevalent joint disease and is one of the major causes of disability in the world. There has been an increase in the incidence of OA, which is associated with an… read more here.
Keywords: fer1l4; expression human; synovial fluid; expression ... See more keywords