Arginase 1 expression is increased during hepatic stellate cell activation and facilitates collagen synthesis.
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DOI: 10.1002/jcb.30403
Abstract: Activation of hepatic stellate cells (HSC) is a key event in the initiation of liver fibrosis. Activated HSCs proliferate and secrete excessive amounts of extracellular matrix (ECM), disturbing liver architecture and function, leading to fibrosis… read more here.
Keywords: arginase; expression increased; hsc activation; expression ... See more keywords
β‐Cell glucokinase expression was increased in type 2 diabetes subjects with better glycemic control
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Diabetes"
DOI: 10.1111/1753-0407.13380
Abstract: Type 2 diabetes (T2D) is characterized by a progressive deterioration of β‐cell function with a continuous decline in insulin secretion. Glucokinase (GCK) facilitates the rate‐limiting step of glycolysis in pancreatic β‐cells, to acquire the proper… read more here.
Keywords: expression increased; type diabetes; type; glucokinase expression ... See more keywords