Triptolide Inhibits Expression of Inflammatory Cytokines and Proliferation of Fibroblast-like Synoviocytes Induced by IL-6/sIL-6R-Mediated JAK2/STAT3 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2021 at "Current Medical Science"
DOI: 10.1007/s11596-020-2302-1
Abstract: Triptolide, a component of the Chinese herb Tripterygium wilfordii Hook F, has been proved to be effective in the treatment of rheumatoid arthritis (RA). However, its underlying mechanisms on RA have not yet been well… read more here.
Keywords: jak2 stat3; expression; expression inflammatory; proliferation ... See more keywords
Effects of Excess Manganese on the Oxidative Status, and the Expression of Inflammatory Factors and Heat Shock Proteins in Cock Kidneys
Sign Up to like & getrecommendations! Published in 2019 at "Biological Trace Element Research"
DOI: 10.1007/s12011-019-02003-y
Abstract: Manganese (Mn) can have adverse effects on organisms as a result of heavy or chronic exposure, including neurological damage. This study examined the effects of chronic exposure to manganese chloride (MnCl2) on various biochemical indices… read more here.
Keywords: expression inflammatory; exposure; heat shock; shock proteins ... See more keywords
Impact of curcumin supplementation on expression of inflammatory transcription factors in hemodialysis patients: A pilot randomized, double-blind, controlled study.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical nutrition"
DOI: 10.1016/j.clnu.2020.03.007
Abstract: BACKGROUND & AIMS Chronic kidney disease (CKD) patients have numerous complications associated with inflammation, which is a potential driver for cardiovascular disease. Curcumin, a compound of the curcuminoid class produced by the Curcuma longa, has… read more here.
Keywords: supplementation; expression inflammatory; expression; transcription factors ... See more keywords
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3
Sign Up to like & getrecommendations! Published in 2018 at "Mechanisms of Ageing and Development"
DOI: 10.1016/j.mad.2017.12.005
Abstract: OBJECTIVE Endothelial cellular senescence is an important contributor to the endothelial dysfunction and atherosclerosis. Our previous studies suggested that salidroside (SAL) can alleviate atherosclerosis and protect endothelial cells against oxidative stress induced damage. However, the… read more here.
Keywords: expression inflammatory; sal; endothelial cellular; senescence ... See more keywords
Vitamin D modulates inflammatory response of DENV-2-infected macrophages by inhibiting the expression of inflammatory-liked miRNAs
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens and Global Health"
DOI: 10.1080/20477724.2022.2101840
Abstract: ABSTRACT Dengue disease caused by dengue virus (DENV) infection is the most common vector-borne viral disease worldwide. Currently, no treatment is available to fight dengue symptoms. We and others have demonstrated the antiviral and immunomodulatory… read more here.
Keywords: denv infection; expression; expression inflammatory; mir ... See more keywords
AB0158 DECREASED AUTOPHAGY IN SALIVARY GLANDS OF PRIMARY SJöGREN’S SYNDROME PATIENTS COULD BE ASSOCIATED WITH AN INCREASED EXPRESSION OF INFLAMMATORY MARKERS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.4740
Abstract: Background: Salivary glands (SG) of primary Sjögren’s syndrome (pSS) patients show high levels of IL-6 and endoplasmic reticulum (ER) stress1. In response to ER stress salivary epithelial cells trigger the unfolded protein response, seeking alleviate… read more here.
Keywords: protein; expression inflammatory; inflammatory; expression ... See more keywords
Anti-Inflammatory Effects and Decreased Formation of Neutrophil Extracellular Traps by Enoxaparin in COVID-19 Patients
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094805
Abstract: Neutrophil Extracellular Traps (NETs) are a contributing factor of vascular thrombosis and alveolar damage in COVID-19 patients. As enoxaparin is currently used to inhibit vascular thrombosis, this study aimed to investigate whether enoxaparin also reduced… read more here.
Keywords: covid patients; enoxaparin pretreatment; extracellular traps; neutrophil extracellular ... See more keywords
Effects of Inflammatory Factor Expression Regulated by 12/15 Lipoxygenase on Obesity-Related Nephropathy
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14132743
Abstract: Background: It has been demonstrated that 12/15-lipoxygenase (LO) contributes to insulin resistance by promoting beta cells’ exposure to inflammation. We investigate the mechanism by which 12/15-LO regulates the expression of inflammatory factors in obesity-related glomerular… read more here.
Keywords: expression; obesity related; inflammatory factors; expression inflammatory ... See more keywords
Mucosal Genes Expression in Inflammatory Bowel Disease Patients: New Insights
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16020324
Abstract: Individual differences in IBD illness severity, behavior, progression, and therapy response are evident. Since a break in the intestinal epithelial barrier causes IBD to begin, mucosal gene expression in IBD is crucial. Due to its… read more here.
Keywords: ibd patients; inflammatory bowel; expression; genes expression ... See more keywords