Integrin β5 and β7 expression in lenalidomide-resistant multiple myeloma cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Hematology"
DOI: 10.1007/s12185-022-03297-w
Abstract: Recently, Hosen N et al. reported frequent expression of activated integrin β7 in multiple myeloma (MM) patients though the clinical significance was not known [1]. They are also conducting a clinical trial using CAR-T-cell therapy… read more here.
Keywords: expression; integrin; expression integrin; lenalidomide resistance ... See more keywords
Expression of αV integrin and its potential partners in bull reproductive tissues, germ cells and spermatozoa.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2022.04.001
Abstract: Integrins are transmembrane receptors expressed in all nucleated mammalian cells, critically involved in cell-matrix adhesion and cell-cell interactions that modulate many signalling cascades. It is assumed that integrins also provide essential functions of the reproductive… read more here.
Keywords: partners bull; integrin potential; reproductive tissues; potential partners ... See more keywords
Expression of integrin αvβ3 in medullary thyroid carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Future Oncology"
DOI: 10.1080/14796694.2024.2376511
Abstract: Aim: Tumor markers often remain elevated after intended curative resection of medullary thyroid carcinoma (MTC). The aim of this study was to determine the expression of αvβ3, a promising theranostics target, in MTC and its… read more here.
Keywords: expression; expression integrin; thyroid carcinoma; medullary thyroid ... See more keywords
Abstract B022: A gradient expression of integrin αvβ6 expression in human cancer cells associates with TGFβ mediated immune evasion
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.canevol23-b022
Abstract: Our previous results demonstrate an integrin-mediated mechanism of immune evasion in colorectal cancer. Increased levels of latent TGFβ in the experimental tumor environment led to the upregulation of the immune checkpoint marker PD-L1 in HCT116WT… read more here.
Keywords: expression integrin; cancer; cell; expression ... See more keywords
Developmentally regulated expression of integrin alpha-6 distinguishes neural crest derivatives in the skin
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1140554
Abstract: Neural crest-derived cells play essential roles in skin function and homeostasis. However, how they interact with environmental cues and differentiate into functional skin cells remains unclear. Using a combination of single-cell data analysis, neural crest… read more here.
Keywords: crest derivatives; neural crest; derivatives skin; crest ... See more keywords