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   Articles with "expression macrophages" as a keyword



Cyclic stretch regulates immune responses via tank‐binding kinase 1 expression in macrophages

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recommendations! Published in 2022 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13526

Abstract: Macrophages distributed in tissues throughout the body contribute to homeostasis. In the inflammatory state, macrophages undergo mechanical stress that regulates the signal transduction of immune responses and various cellular functions. However, the effects of the… read more here.

Keywords: stretch; immune responses; cyclic stretch; tank binding ... See more keywords

Differential phagocytic expression of IC‐21 macrophages and their scavenging receptors during inflammatory induction by oxysterol: A microscopic approach

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recommendations! Published in 2024 at "Microscopy Research and Technique"

DOI: 10.1002/jemt.24647

Abstract: Phagocytosis by macrophages dates back to a long history in science, this present study deals with new approaches that have been analyzed and standardized towards the interesting aspects of primary and secondary macrophages. The distinct… read more here.

Keywords: macrophages scavenging; scavenging receptors; differential phagocytic; phagocytic expression ... See more keywords
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Extracellular vesicles derived from lung cancer cells exposed to intermittent hypoxia upregulate programmed death ligand 1 expression in macrophages

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recommendations! Published in 2021 at "Sleep and Breathing"

DOI: 10.1007/s11325-021-02369-1

Abstract: Intermittent hypoxia (IH), a hallmark of obstructive sleep apnea (OSA), compromises immune surveillance through the upregulation of programmed cell death-1 ligand (PD-L1). Tumor-released extracellular vesicles (EVs) have been reported to modulate immunosuppressive activities. We investigated… read more here.

Keywords: hypoxia; expression macrophages; cancer cells; lung cancer ... See more keywords

Pseudomonas aeruginosa increases MUC1 expression in macrophages through the TLR4-p38 pathway.

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recommendations! Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.08.056

Abstract: Alveolar macrophages (AMs) play a critical role in the clearance of Pseudomonas aeruginosa (Pa) from the airways. However, hyper-activation of macrophages can impair bacterial clearance and contribute to morbidity and mortality. MUC1 mucin is a… read more here.

Keywords: expression macrophages; pseudomonas aeruginosa; muc1 expression; tlr4 p38 ... See more keywords

Myeloma-derived IL-32γ induced PD-L1 expression in macrophages facilitates immune escape via the PFKFB3-JAK1 axis

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recommendations! Published in 2022 at "Oncoimmunology"

DOI: 10.1080/2162402x.2022.2057837

Abstract: ABSTRACT Multiple myeloma (MM) is characterized by an accumulation of monoclonal plasma cells within the bone marrow (BM). Macrophages are an abundant component of myeloma BM microenvironment and support survival of the malignant cells and… read more here.

Keywords: myeloma; expression; jak1 axis; expression macrophages ... See more keywords

Tannerella forsythia strains differentially induce interferon gamma-induced protein 10 (IP-10) expression in macrophages due to lipopolysaccharide heterogeneity.

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recommendations! Published in 2022 at "Pathogens and disease"

DOI: 10.1093/femspd/ftac008

Abstract: Tannerella forsythia is strongly implicated in the development of periodontitis, an inflammatory disease that destroys the bone and soft tissues supporting the tooth.  To date, the knowledge of the virulence attributes of T. forsythia species… read more here.

Keywords: heterogeneity; expression; forsythia; tannerella forsythia ... See more keywords

TGF-β1 induces PD-1 expression in macrophages through SMAD3/STAT3 cooperative signaling in chronic inflammation

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recommendations! Published in 2024 at "JCI Insight"

DOI: 10.1172/jci.insight.165544

Abstract: Programmed cell death protein 1 (PD-1), a coinhibitory T cell checkpoint, is also expressed on macrophages in pathogen- or tumor-driven chronic inflammation. Increasing evidence underscores the importance of PD-1 on macrophages for dampening immune responses.… read more here.

Keywords: smad3 stat3; tgf; chronic inflammation; expression ... See more keywords

Alpha-Momorcharin Inhibits Proinflammatory Cytokine Expression by M1 Macrophages but Not Anti-Inflammatory Cytokine Expression by M2 Macrophages

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recommendations! Published in 2022 at "Journal of Inflammation Research"

DOI: 10.2147/jir.s372306

Abstract: Background Alpha-momorcharin (α-MMC) is a natural medicine derived from bitter melon and has been found to exert immunomodulatory effects. Our previous study indicated that α-MMC can regulate cytokine release from monocytes, but it remains unknown… read more here.

Keywords: expression; anti inflammatory; cytokine expression; expression macrophages ... See more keywords