Bile duct ligation causes opposite impacts on the expression and function of BCRP and P-gp in rat brain partly via affecting membrane expression of ezrin/radixin/moesin proteins.
Sign Up to like & getrecommendations! Published in 2021 at "Acta pharmacologica Sinica"
DOI: 10.1038/s41401-020-00602-3
Abstract: Breast cancer resistance protein (BCRP) and P-glycoprotein (P-gp) are co-located at blood-brain barrier (BBB) cells, preventing their substrates from entering brain. Accumulating evidence demonstrates that liver failure impairs P-gp and BCRP expression and function in… read more here.
Keywords: protein; expression membrane; bcrp; expression ... See more keywords
Elevated expression of the membrane-anchored serine protease TMPRSS11E in NSCLC progression.
Sign Up to like & getrecommendations! Published in 2022 at "Carcinogenesis"
DOI: 10.1093/carcin/bgac069
Abstract: TMPRSS11E was found to be upregulated in human non-small cell lung cancer samples (NSCLC) and cell lines, and high expression was associated with poor survival of NSCLC patients. The results of in vitro and in… read more here.
Keywords: elevated expression; expression membrane; expression; catalytic domain ... See more keywords