The Effect of Chronic Mild Stress and Venlafaxine on the Expression and Methylation Levels of Genes Involved in the Tryptophan Catabolites Pathway in the Blood and Brain Structures of Rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-020-01563-2
Abstract: A growing body of evidence suggests that depression may be associated with impairment of the tryptophan catabolites (TRYCATs) pathway. The present study investigated the effects of the chronic administration of venlafaxine on the expression and… read more here.
Keywords: tryptophan catabolites; expression methylation; methylation; venlafaxine ... See more keywords
Mining pathway associations for disease-related pathway activity analysis based on gene expression and methylation data
Sign Up to like & getrecommendations! Published in 2017 at "BioData Mining"
DOI: 10.1186/s13040-017-0127-7
Abstract: BackgroundThe problem of discovering genetic markers as disease signatures is of great significance for the successful diagnosis, treatment, and prognosis of complex diseases. Even if many earlier studies worked on identifying disease markers from a… read more here.
Keywords: expression methylation; gene expression; disease; pathway ... See more keywords
Inferring Functional Epigenetic Modules by Integrative Analysis of Multiple Heterogeneous Networks
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.706952
Abstract: Gene expression and methylation are critical biological processes for cells, and how to integrate these heterogeneous data has been extensively investigated, which is the foundation for revealing the underlying patterns of cancers. The vast majority… read more here.
Keywords: expression methylation; methylation; epigenetic modules; gene ... See more keywords
Prognostic Effect of Inflammatory Genes on Stage I–III Colorectal Cancer—Integrative Analysis of TCGA Data
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DOI: 10.3390/cancers13040751
Abstract: Simple Summary Research interest in the role of inflammation in the progression and prognosis of colorectal cancer (CRC) is growing. In this study, we evaluated the expression and DNA methylation levels of inflammation-related genes in… read more here.
Keywords: expression methylation; methylation; analysis; crc ... See more keywords