MiR‐17‐3p inhibits osteoblast differentiation by downregulating Sox6 expression
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12979
Abstract: Osteoporosis and osteoarthritis are orthopedic disorders that affect millions of elderly people worldwide; stimulation of bone formation is a potential therapeutic strategy for the treatment of these conditions. As the only bone‐forming cells, osteoblasts play… read more here.
Keywords: mir; differentiation; role; osteoblast differentiation ... See more keywords
PARP‐1 modulates the expression of miR‐223 through histone acetylation to involve in the hydroquinone‐induced carcinogenesis of TK6 cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23142
Abstract: The upstream regulators of microRNAs were rarely reported. Hydroquinone (HQ) is the main metabolite of benzene, one of the important environmental factors contributing to leukemia and lymphoma. In HQ‐induced malignant transformed TK6 (TK6‐HT) cells, the… read more here.
Keywords: expression mir; tk6 cells; hydroquinone; mir 223 ... See more keywords
Genipin inhibits the scleral expression of miR-29 and MMP2 and promotes COL1A1 expression in myopic eyes of guinea pigs
Sign Up to like & getrecommendations! Published in 2020 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-020-04634-7
Abstract: Purpose High myopia can lead to blindness. Genipin is a collagen cross-linking agent that may be used to treat myopia. However, the mechanism of action of genipin for the treatment of myopia is unclear. This… read more here.
Keywords: guinea; col1a1 expression; scleral expression; mir ... See more keywords
Expression of miR-210 in the peripheral blood of patients with newly diagnosed type 2 diabetes mellitus and its effect on the number and function of endothelial progenitor cells.
Sign Up to like & getrecommendations! Published in 2020 at "Microvascular research"
DOI: 10.1016/j.mvr.2020.104032
Abstract: OBJECTIVE This study aims to investigate the correlation between the expression of miR-210 in peripheral blood and the number of peripheral endothelial progenitor cells (EPCs) in patients with type 2 diabetes mellitus (T2DM). We also… read more here.
Keywords: group; number; peripheral blood; mir 210 ... See more keywords
Downregulation of miR-424 in placenta is associated with severe preeclampsia.
Sign Up to like & getrecommendations! Published in 2019 at "Pregnancy hypertension"
DOI: 10.1016/j.preghy.2019.05.017
Abstract: Previous studies have suggested that altered miRNA expression in the placenta is associated with preeclampsia. The aim of this study was to investigate the expression of miR-424 in placental samples of severe preeclampsia (sPE) and… read more here.
Keywords: expression; placenta associated; mir 424; severe preeclampsia ... See more keywords
MiR-142-5p act as an oncogenic microRNA in colorectal cancer: Clinicopathological and functional insights.
Sign Up to like & getrecommendations! Published in 2018 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2018.01.006
Abstract: OBJECTIVES miR-142-5p was noted aberrantly expressed and plays important roles in different pathophysiological conditions in human. The present study aims to examine the expression of miR-142-5p and its association with clinicopathological factors in a large… read more here.
Keywords: cancer; expression mir; colorectal cancer; mir 142 ... See more keywords
Expression of miR-181a in Circulating Tumor Cells of Ovarian Cancer and Its Clinical Application
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DOI: 10.1021/acsomega.1c02425
Abstract: Objective: To determine the possibility of early diagnosis and prognosis of ovarian cancer (OC) via detecting miR-181a in circulating tumor cells (CTCs) of OC and to solve clinical difficulties in OC tissue sample collection. Methods:… read more here.
Keywords: 181a circulating; circulating tumor; expression; ovarian cancer ... See more keywords
The expression of miR-129-5p and its target genes in the skin of goats
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DOI: 10.1080/10495398.2020.1730392
Abstract: Abstract Coat color is one of the major quality traits of animals, and miR-129-5p acts as an important regulator for melanin biosynthesis in mammals. In this study, real-time PCR and western blotting were used to… read more here.
Keywords: target genes; genes skin; mir 129; coat color ... See more keywords
Differential Expression of miR-202 and Validation of Predicted Target Genes in the Skin Tissue of C57BL/6 Black Mice and BALB/c White Mice.
Sign Up to like & getrecommendations! Published in 2017 at "DNA and cell biology"
DOI: 10.1089/dna.2016.3613
Abstract: In recent years, with the need of the fur industry to obtain greater quantities of high-quality fur and the research of hair follicle development attracting greater attention, the role of miRNAs in hair follicle development… read more here.
Keywords: skin tissue; target; mice; mir 202 ... See more keywords
Aberrant Expression of miR-323a-5p in Patients with Refractory Epilepsy Caused by Focal Cortical Dysplasia.
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DOI: 10.1089/gtmb.2016.0096
Abstract: BACKGROUND Epilepsy remains one of the most common clinical neurological disorders. About a third of patients with epilepsy are refractory to drug treatment, mainly as a result of focal cortical dysplasia (FCD). In this study,… read more here.
Keywords: refractory epilepsy; mir 323a; expression; patients refractory ... See more keywords
A1668 Expression of miR-139–3p in apoptotic neonatal rat cardiomyocytes induced by hypoxia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000548055.20178.1e
Abstract: Objectives: Myocardial cell apoptosis plays a key role in the development of heart failure. Compared with normal myocardial cells, the hypertrophy myocardial cell apoptosis rate increased significantly, as well as their sensitivity to apoptosis stimulating… read more here.
Keywords: mir 139; cardiomyocytes induced; 139 apoptotic; group ... See more keywords