Strong cytoplasmic ETV1 expression has a negative impact on prostate cancer outcome
Sign Up to like & getrecommendations! Published in 2019 at "Virchows Archiv"
DOI: 10.1007/s00428-019-02573-1
Abstract: Overexpression of ETS genes is involved in prostate cancer (PrCa), but there is little information on the non-ERG components of this family. We have investigated ETV1, ETV4, and ETV5 overexpression, with or without PTEN loss,… read more here.
Keywords: expression negative; overexpression; etv1; prostate cancer ... See more keywords
Implication of reward alterations in the expression of negative symptoms in 22q11.2 deletion syndrome: a behavioural and DTI study
Sign Up to like & getrecommendations! Published in 2017 at "Psychological Medicine"
DOI: 10.1017/s0033291716003482
Abstract: Background Alterations of the reward system have been proposed as one of the core mechanisms underlying the expression of negative symptoms in schizophrenia. Specifically, deficits in specific reward components and white matter (WM) integrity of… read more here.
Keywords: deletion syndrome; pleasure; negative symptoms; expression negative ... See more keywords
Leishmania infantum induces expression of the negative regulatory checkpoint, CTLA‐4, by human naïve CD8+ T cells
Sign Up to like & getrecommendations! Published in 2019 at "Parasite Immunology"
DOI: 10.1111/pim.12659
Abstract: CD8+ T cells are important in mediating protective responses to intracellular pathogens. However, an uncontrolled response may lead to pathology. The role of CD8+ T cells in different clinical manifestations of human leishmaniasis is controversial… read more here.
Keywords: cd8; expression negative; cd8 cells; infantum induces ... See more keywords
Smoking History Predicts High Presence of TILs and Efficacy of PD-1 Blockade in PD-L1 Expression-negative Non-small Cell Lung Cancer Patients
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DOI: 10.21873/anticanres.15390
Abstract: Background/Aim: Programmed death-ligand 1 (PD-L1) expression on tumor cells is a predictive biomarker of programmed cell death 1 (PD-1) blockade therapy. This study sought to clarify predictors of the efficacy of nivolumab in non-small cell… read more here.
Keywords: expression negative; history; smoking history; non small ... See more keywords