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Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25813
Abstract: Osteoporosis is one of the most prevalent ageing‐associated diseases that are soaring in the modern world. Although various aspects of the disease have been investigated to understand the bases of osteoporosis, the pathophysiological mechanisms underlying…
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Keywords:
expression osteoblasts;
poldip2;
expression;
poldip2 expression ... See more keywords
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1
Published in 2019 at "Current Genomics"
DOI: 10.2174/1389202920666190422142053
Abstract: Background: Microgravity (μG) negatively influences bone metabolism by affecting normal osteoblast and osteoclast function. μG effects on bone metabolism has been an extensive field of study in recent years, due to the challenges presented by…
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Keywords:
osteoclasts microgravity;
expression osteoblasts;
gene expression;
expression ... See more keywords
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1
Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13060891
Abstract: In osteoarthritis (OA), bone changes are radiological hallmarks and are considered important for disease progression. The C-C chemokine receptor-2 (CCR2) has been shown to play an important role in bone physiology. In this study, we…
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Keywords:
damage;
ccr2;
bone;
chemokine receptor ... See more keywords
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Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21217905
Abstract: Multiple myeloma (MM)-induced bone disease occurs through hyperactivation of osteoclasts by several factors secreted by MM cells. MM cell-secreted factors induce osteoclast differentiation and activation via direct and indirect actions including enhanced expression of receptor…
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Keywords:
expression osteoblasts;
expression;
hgf;
bone disease ... See more keywords
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1
Published in 2020 at "International Journal of Medical Sciences"
DOI: 10.7150/ijms.44612
Abstract: Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory disease, in which the immune system attacks joint tissue. Interleukin (IL)-6 is a key proinflammatory cytokine in RA progression. Sphingosine-1-phosphate (S1P), a platelet-derived lysophospholipid mediator, reportedly regulates…
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Keywords:
mek erk;
expression osteoblasts;
pi3k mek;
erk signaling ... See more keywords