Expression of the prognostic marker IL‐8 correlates with the immune signature and epithelial‐mesenchymal transition in breast cancer
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24797
Abstract: IL‐8 has been implicated in the malignant progression of various types of cancers; however, the precise molecular mechanisms associated with IL‐8 in breast cancer (BRCA) are unclear. read more here.
Keywords: expression prognostic; breast; prognostic marker; marker correlates ... See more keywords
Loss of STING expression is prognostic in non–small cell lung cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.26804
Abstract: Stimulator of interferon (IFN) genes (STING) is a protein that promotes type I IFN production essential for T‐cell activation. In this study, we aim to characterize STING expression comprehensively using The Cancer Genome Atlas (TCGA)… read more here.
Keywords: loss sting; cell; sting expression; expression prognostic ... See more keywords
Tumor cell proliferation (Ki-67) expression and its prognostic significance in histological subtypes of lung adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Lung cancer"
DOI: 10.1016/j.lungcan.2021.02.009
Abstract: OBJECTIVES Ki-67 is a key molecular marker to indicate the proliferative activity of tumor cells in lung cancer. However, Ki-67 expression and its prognostic significance in histological subtypes of lung adenocarcinoma (LUAD) remain unclear. MATERIALS… read more here.
Keywords: histological subtypes; expression prognostic; subtypes lung; expression ... See more keywords
Comprehensive Analysis of Expression and Prognostic Value of Selenoprotein Genes in Thyroid Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Genetic testing and molecular biomarkers"
DOI: 10.1089/gtmb.2021.0123
Abstract: Background: Low selenium levels are associated with an increased incidence and advanced stage of thyroid cancers (THCAs). In response to changes in selenium levels, a hierarchy of selenoprotein biosynthesis allows tissue-specific fine-tuning of the 25… read more here.
Keywords: biological processes; correlated genes; expression prognostic; analysis expression ... See more keywords
Expression and prognostic impact of alpha thalassemia/mental retardation X-linked and death domain-associated protein in human lung cancer
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DOI: 10.1097/md.0000000000016712
Abstract: Supplemental Digital Content is available in the text read more here.
Keywords: alpha thalassemia; impact alpha; prognostic impact; mental retardation ... See more keywords
Expression, prognostic significance and therapeutic implications of PD-L1 in gliomas.
Sign Up to like & getrecommendations! Published in 2021 at "Neuropathology and applied neurobiology"
DOI: 10.1111/nan.12767
Abstract: The advent of checkpoint immunotherapy, particularly with programmed death-1 (PD-1) and programmed death-ligand 1 (PD-L1) inhibitors, has provided ground-breaking results in several advanced cancers. Substantial efforts are being made to extend these promising therapies to… read more here.
Keywords: therapeutic implications; expression prognostic; significance therapeutic; expression ... See more keywords
Expression and Prognostic Value of Lgr5 in Patients with Recurrent Nasopharyngeal Carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s408991
Abstract: Background As a cancer stem cells (CSCs) surface marker, Lgr5 plays an important role in the signal transduction of cancer cells and is a potential biomarker for cancer diagnosis and prognosis. However, the expression and… read more here.
Keywords: lgr5; rnpc; expression prognostic; expression ... See more keywords
Comprehensive Analysis of the Differential Expression and Prognostic Value of Histone Deacetylases in Glioma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.840759
Abstract: Gliomas are the most common and aggressive malignancies of the central nervous system. Histone deacetylases (HDACs) are important targets in cancer treatment. They regulate complex cellular mechanisms that influence tumor biology and immunogenicity. However, little… read more here.
Keywords: differential expression; histone deacetylases; glioma; expression prognostic ... See more keywords
Impact of PD-L1 and PD-1 Expression on the Prognostic Significance of CD8+ Tumor-Infiltrating Lymphocytes in Non-Small Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.680973
Abstract: The immune infiltrate within tumors has proved to be very powerful in the prognostic stratification of patients and much attention is also being paid towards its predictive value. In this work we therefore aimed at… read more here.
Keywords: impact expression; cd8 tumor; cd8; expression prognostic ... See more keywords
Expression and Prognostic Value of MCM Family Genes in Osteosarcoma
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.668402
Abstract: We performed a detailed cancer VS normal analysis to explore the expression and prognostic value of minichromosome maintenance (MCM) proteinsin human sarcoma. The mRNA expression levels of the MCM family genes in sarcoma were analyzed… read more here.
Keywords: sarcoma; prognostic value; expression prognostic; value ... See more keywords
Expression and Prognostic Implication of PD-L1 in Patients with Urothelial Carcinoma with Variant Histology (Squamous Differentiation or Micropapillary) Undergoing Radical Cystectomy
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10040910
Abstract: The expression and prognostic role of programmed death ligand-1 (PD-L1) on tumor-infiltrating immune cells (TICs) has not been determined in urothelial carcinoma (UC) with variant histology. We retrospectively reviewed 90 patients (44 with micropapillary variant… read more here.
Keywords: expression prognostic; expression; carcinoma variant; urothelial carcinoma ... See more keywords