Mitochondrial serine hydroxymethyltransferase 2 is a potential diagnostic and prognostic biomarker for human glioma
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Neurology and Neurosurgery"
DOI: 10.1016/j.clineuro.2017.01.005
Abstract: OBJECTIVE Scholars have gradually come to appreciate the relevance of serine and glycine metabolism. Recently, researchers have discovered that mitochondrial serine hydroxymethyltransferase 2 (SHMT2) is overexpressed in various types of cancer. However, the function of… read more here.
Keywords: expression shmt2; mitochondrial serine; glioma; shmt2 ... See more keywords
High expression of SHMT2 is correlated with tumor progression and predicts poor prognosis in gastrointestinal tumors.
Sign Up to like & getrecommendations! Published in 2019 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201911_19431
Abstract: OBJECTIVE Gastrointestinal tumors are malignant tumors with high morbidity. Mitochondrial serine hydroxymethyltransferase 2 (SHMT2) is a key enzyme in the synthesis of serine and glycine, which has prognostic and therapeutic value for many malignant tumors. However, the… read more here.
Keywords: gastrointestinal tumors; shmt2 expression; shmt2; expression ... See more keywords
Increased Expression of SHMT2 Is Associated With Poor Prognosis and Advanced Pathological Grade in Oral Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.588530
Abstract: This study focused on the expression of mitochondrial serine hydroxymethyltransferase (SHMT2) in oral squamous cell carcinoma (OSCC) and its correlation with clinical traits and the prognosis of OSCC patients. Immunochemical staining and Western blotting were… read more here.
Keywords: oral squamous; prognosis; squamous cell; shmt2 ... See more keywords