Expression of Single Chain Variable Fragment (scFv) Molecules in Plants: A Comprehensive Update
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biotechnology"
DOI: 10.1007/s12033-020-00241-3
Abstract: Single chain variable fragments (scFvs) are generated by joining together the variable heavy and light chain of a monoclonal antibody (mAb) via a peptide linker. They offer some advantages over the parental mAb such as… read more here.
Keywords: chain; expression single; scfv; expression ... See more keywords
A Bayesian mixture model for the analysis of allelic expression in single cells
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-13099-0
Abstract: Allele-specific expression (ASE) at single-cell resolution is a critical tool for understanding the stochastic and dynamic features of gene expression. However, low read coverage and high biological variability present challenges for analyzing ASE. We demonstrate… read more here.
Keywords: mixture model; expression single; expression; allelic expression ... See more keywords
Sci-fate characterizes the dynamics of gene expression in single cells
Sign Up to like & getrecommendations! Published in 2020 at "Nature biotechnology"
DOI: 10.1038/s41587-020-0480-9
Abstract: Gene expression programs change over time, differentiation and development, and in response to stimuli. However, nearly all techniques for profiling gene expression in single cells do not directly capture transcriptional dynamics. In the present study,… read more here.
Keywords: expression single; single cells; gene expression; sci fate ... See more keywords