Modulatory Effects of Fingolimod (FTY720) on the Expression of Sphingolipid Metabolism-Related Genes in an Animal Model of Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-1040-x
Abstract: Sphingolipid signaling disturbances correlate with Alzheimer’s disease (AD) progression. We examined the influence of FTY720/fingolimod, a sphingosine analog and sphingosine-1-phosphate (S1P) receptor modulator, on the expression of sphingolipid metabolism and signaling genes in a mouse… read more here.
Keywords: expression sphingolipid; alzheimer disease; sphingolipid metabolism; model ... See more keywords
Gene expression of sphingolipid metabolism pathways is altered in hidradenitis suppurativa
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2017.03.016
Abstract: Background Hidradenitis suppurativa (HS) is a debilitating skin disease characterized by painful recurrent nodules and abscesses caused by chronic inflammation. Early events in the development of HS are believed to occur in the folliculopilosebaceous unit;… read more here.
Keywords: gene expression; expression; expression sphingolipid; sphingolipid metabolism ... See more keywords