Biphasic prognostic significance of PD-L1 expression status in patients with early- and locally advanced-stage non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02755-w
Abstract: Programmed cell death-ligand 1 (PD-L1) expression on tumor cells is induced by interferon-gamma, suggesting the induction of an anti-tumor immune response. In turn, binding of PD-L1 to programmed cell death 1 (PD-1) triggers an immune… read more here.
Keywords: cell; expression status; expression; cancer ... See more keywords
A Coclinical Radiogenomic Validation Study: Conserved Magnetic Resonance Radiomic Appearance of Periostin-Expressing Glioblastoma in Patients and Xenograft Models
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-17-3420
Abstract: Purpose: Radiomics is the extraction of multidimensional imaging features, which when correlated with genomics, is termed radiogenomics. However, radiogenomic biological validation is not sufficiently described in the literature. We seek to establish causality between differential… read more here.
Keywords: postn expression; radiomic features; validation; expression status ... See more keywords
Expression Status of Prohibitin Gene Predicts the Prognosis of Acute Myeloid Leukemia with Normal Cytogenetics
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-115726
Abstract: Introduction: Cytogenetically normal acute myeloid leukemia (CN-AML) accounts for 40 to 50 percent of all AML and shows significant heterogeneity in clinical outcomes. Despite the advancements in the molecular pathophysiology of CN-AML, clinical outcome of… read more here.
Keywords: expression status; expression; aml; leukemia ... See more keywords
Deep learning radiomics model based on breast ultrasound video to predict HER2 expression status
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1144812
Abstract: Purpose The detection of human epidermal growth factor receptor 2 (HER2) expression status is essential to determining the chemotherapy regimen for breast cancer patients and to improving their prognosis. We developed a deep learning radiomics… read more here.
Keywords: breast; expression status; her2 expression; model ... See more keywords
Cost-Effectiveness Analysis of Atezolizumab Versus Chemotherapy as First-Line Treatment for Metastatic Non-Small-Cell Lung Cancer With Different PD-L1 Expression Status
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.669195
Abstract: Background Atezolizumab could significantly improve clinical outcomes and was associated with less toxicity compared with chemotherapy as the first-line treatment of PD-L1-selected patients with EGFR and ALK wild-type metastatic non-small-cell lung cancer (NSCLC). However, the… read more here.
Keywords: chemotherapy; first line; expression status; atezolizumab ... See more keywords
CT Image-Based Biopsy to Aid Prediction of HOPX Expression Status and Prognosis for Non-Small Cell Lung Cancer Patients
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15082220
Abstract: Simple Summary Recent studies have found that the HOPX gene functions as a tumor suppressor, and its expression status influences patients’ survival in NSCLC. However, the gene expression derived from the wet biopsy sampling has… read more here.
Keywords: status prognosis; expression; hopx expression; biopsy ... See more keywords
High TLR6 Expression Status Predicts a More Favorable Prognosis after Esophagectomy for Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Current Oncology"
DOI: 10.3390/curroncol30050356
Abstract: Most so-called “beneficial bacteria” in gut microbiota are Gram-positive, and TLR6 recognizes the peptidoglycan (PGN) present in their cell walls. We hypothesized that a high TLR6 expression status predicts a more favorable prognosis after esophagectomy.… read more here.
Keywords: high tlr6; tlr6 expression; expression status; expression ... See more keywords
MKX-AS1 Gene Expression Associated with Variation in Drug Response to Oxaliplatin and Clinical Outcomes in Colorectal Cancer Patients
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DOI: 10.3390/ph16050757
Abstract: Oxaliplatin (OXAL) is a commonly used chemotherapy for treating colorectal cancer (CRC). A recent genome wide association study (GWAS) showed that a genetic variant (rs11006706) in the lncRNA gene MKX-AS1 and partnered sense gene MKX… read more here.
Keywords: mkx as1; response; expression; gene ... See more keywords
Quantitative parameters in novel spectral computed tomography: Assessment of Ki-67 expression in patients with gastric adenocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v29.i10.1602
Abstract: BACKGROUND The level of Ki-67 expression has served as a prognostic factor in gastric cancer. The quantitative parameters based on the novel dual-layer spectral detector computed tomography (DLSDCT) in discriminating the Ki-67 expression status are… read more here.
Keywords: gastric adenocarcinoma; status; expression; zeff ... See more keywords